ArticleClinical interventions in aging2025
Development of an Online Nomogram for Predicting Postoperative Hypoalbuminemia in Older Adults Following Femoral Neck Fractures.
Article in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Interpretable machine learning model for predicting postoperative hypoproteinemia in middle-aged and elderly patients following total joint arthroplasty: a multicenter retrospective study.Frontiers in nutrition · 2026Article
- Comparative study on the clinical efficacy of femoral neck system and cannulated cancellous screw in the treatment of femoral neck fractures in young patients.BMC musculoskeletal disorders · 2025Article
- Risk factors and predictive nomogram of human serum albumin infusion after total hip arthroplasty for femoral head necrosis.European journal of medical research · 2025Article
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5 authors.
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Abstract
Objective: Postoperative hypoalbuminemia after total hip arthroplasty (THA) in older adults with femoral neck fractures can increase the risk of postoperative infection and lengthen hospital stays. The purpose of this study was to construct an online nomogram that can be used for the clinical preoperative assessment of older adults to reduce the incidence of postoperative complications. Methods: This study included older adults who underwent THA for femoral neck fracture at Northern Jiangsu People's Hospital between December 2018 and April 2022. Univariate and multivariate logistic regression analyses were performed for the training cohort to identify independent risk factors. The area under the ROC curve (AUC), calibration curve, and decision curve analysis (DCA) of the training group (n=306) and the validation group (n=131) were plotted to assess the model performance. Results: Multivariate logistic regression analysis revealed 5 independent risk factors, including Age, body mass index (BMI), surgery time, preoperative blood calcium level, and preoperative erythrocyte sedimentation rate (ESR). We constructed a nomogram, and the area under the curve (AUC) of the nomogram was 0.763 (95% CI 0.705-0.820) for the training group and 0.750 (95% CI 0.665-0.835) for the validation group. The calibration curve showed good consistency between the predicted and actual probabilities. Decision curve analysis (DCA) showed that using the nomogram had a high net benefit. Conclusion: Old age, lower BMI, longer surgery time, preoperative blood calcium level and preoperative ESR are independent risk factors for postoperative hypoalbuminemia after THA in older adults with femoral neck fractures. The online nomogram had high predictive values for to predict clinical postoperative hypoalbuminemia older adults with femoral neck fracture.
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