ArticleFrontiers in endocrinology2025
BMI trajectories among children diagnosed with type 1 diabetes mellitus at a tertiary diabetes center.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The incidence of type 1 diabetes mellitus (T1DM) has increased worldwide, raising concerns about the intersection between T1DM and the rising prevalence of childhood obesity. This study investigates secular trends in body mass index (BMI) at T1DM diagnosis and its trajectory post-diagnosis, focusing on predictors of obesity persistence. Methods: This retrospective cohort study was conducted at a tertiary diabetes center in Riyadh, Saudi Arabia, between January 2015 and December 2023. Children under 14 years diagnosed with T1DM at the center were included, while those diagnosed elsewhere or with other diabetes types were excluded. Data included demographics, BMI z-scores based on Saudi and CDC growth charts, HbA1c levels, and clinical presentations like diabetic ketoacidosis (DKA). Linear regression assessed secular trends and predictors of baseline BMI z-scores. Results: Among 1160 screened children's charts, 408(35.17%) children met inclusion criteria. At diagnosis, mean age was 7.87 ± 3.53 years, with 161 (39.5%) presenting with DKA. The mean baseline BMI was 16.06 ± 3.62 kg/m², and BMI z-scores were -0.22 ± 1.65 (Saudi growth references) and -0.87 ± 1.92 (CDC growth references). No significant secular trends in BMI z-scores, gender, or DKA presentation were observed. Of 59(14.46%) children with baseline overweight/obesity, 46 (77.97%) remained overweight/obese at follow-up (p<0.001). The mean BMI z-score increased to 1.14± 1.64 at follow-up, with 113(27.70%) meeting overweight/obesity criteria. Conclusion: Overweight/obesity at diagnosis with T1DM persists at follow-up. Addressing obesity at T1DM diagnosis is crucial for mitigating its long-term metabolic impact. Future research should target interventions addressing lifestyle factors contributing to obesity in children with T1DM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.