Evidence map›Paper›PMID 40166616›Full record

ArticleFrontiers in aging neuroscience2025

Linking cognitive reserve to neuropsychological outcomes and resting-state frequency bands in healthy aging.

Vanesa Perez, Vanesa Hidalgo, Alicia Salvador

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vanesa PerezLaboratory of Social Cognitive Neuroscience, Department of Psychobiology, IDOCAL, University of Valencia, Valencia, Spain.
Vanesa HidalgoLaboratory of Social Cognitive Neuroscience, Department of Psychobiology, IDOCAL, University of Valencia, Valencia, Spain.
Alicia SalvadorLaboratory of Social Cognitive Neuroscience, Department of Psychobiology, IDOCAL, University of Valencia, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: As the proportion of older people has surged in the past 100 years, healthy aging has emerged as a crucial topic in neuroscience research. This study aimed to investigate the spectral power of EEG frequency bands during resting-state in older people with high and low cognitive reserve (CR). Methods: To do so, 74 healthy older people (55-74 years old) were recruited and divided into two groups based on their level of CR: high CR ( Results: Neuropsychological tests did not reveal significant differences between the two groups on most of the cognitive measures. However, the EEG analysis showed that individuals with high CR exhibited lower spectral power in the theta and delta frequency bands across different brain regions, compared to those with low CR. Discussion: These findings suggest that individuals with high CR tend to function more efficiently, relying on fewer neural resources to sustain cognitive performance. In contrast, those with low CR may engage compensatory neural mechanisms, as indicated by increased spectral power while resting, conceivably reflecting the brain's effort to preserve cognitive function.

Indexed as

cognitive reserveelectroencephalographyfrequency bandshealthy agingneuropsychological assessment

Identifiers

PMID40166616
PMCPMC11955703

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.