ArticleCureus2025
Characteristics of Patients Undergoing Laparoscopic Hysterectomy for Atypical Endometrial Hyperplasia.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
objectiveThis study aimed to investigate the potential risk of a final pathological diagnosis of endometrial cancer in laparoscopic surgery for preoperatively diagnosed atypical endometrial hyperplasia (AEH), considering literature reports indicating a 40% coexistence rate of AEH with endometrial cancer. METHODOLOGY: A retrospective analysis was conducted on 17 patients with preoperative AEH undergoing laparoscopic surgery at our hospital. The median age was 50 (37-74) years, and the median body mass index (BMI) was 25.1 (16.9-44.3) kg/m
resultsPostoperative diagnoses were AEH in 10 cases, atypical polypoid adenomyoma (APAM) in one case, and endometrial cancer in six cases. Comparison between the AEH group and the endometrial cancer group showed that the proportion of postmenopausal women was higher in the endometrial cancer group (33.3% vs. 66.7%), as was the presence of endometrial thickening on imaging (20% vs. 66.7%), although these differences were not statistically significant. However, patients in the endometrial cancer group were significantly older than those in the AEH group (median age: 59.5 vs. 47.5 years,
conclusionsDespite nonsignificant differences in factors other than age, our study underscores the critical consideration of endometrial cancer during laparoscopic surgery for AEH, even with comprehensive preoperative examinations. This emphasizes the need for vigilant management strategies and heightened awareness of the surgical approach to AEH cases.
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