Evidence map›Paper›PMID 40166507›Full record

ArticleCureus2025

Tumoral Calcinosis of the Thoracolumbar Spine Associated With Adjacent Segment Degeneration After Lumber Fusion: A Case of Myelopathy.

Yu Kobayashi, Takaki Inoue, Hiroyuki Motegi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu KobayashiDepartment of Orthopaedic Surgery, Chiba Aoba Municipal Hospital, Chiba, JPN.
Takaki InoueDepartment of Orthopaedic Surgery, Chiba Aoba Municipal Hospital, Chiba, JPN.
Hiroyuki MotegiDepartment of Orthopaedic Surgery, Chiba Aoba Municipal Hospital, Chiba, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumoral calcinosis is characterized by the deposition of calcified masses in peri-articular tissues, typically near joints. Spinal involvement is rare, particularly following adjacent segment degeneration (ASD) after lumbar spinal fusion. We present the case of a 73-year-old female who developed tumoral calcinosis with myelopathy following lumbar fusion surgery. She had previously undergone two lumbar spine surgeries, which resulted in lumbar fusion from L2 to L5. She developed lower back and leg pain, which progressively worsened, eventually leading to bilateral lower limb paralysis, paresthesia, bladder and rectal dysfunction, and gait disturbance. Computed tomography revealed calcified lesions at the T12-L1 segment adjacent to the spinal fusion. Surgical treatment included laminectomy with resection of the calcified lesions for decompression and extended fusion for stabilization. Complete removal of the calcified lesions via a posterior approach was challenging due to its extensive anterior involvement; therefore, partial resection was performed. A white calcified substance was extracted from the lesion, and ultrasound confirmed adequate decompression of the spinal cord. Postoperatively, the patient showed significant neurological improvement, and follow-up imaging showed no progression of the calcified lesion. This case highlights the importance of considering tumoral calcinosis in the differential diagnosis of spinal cord compression following ASD after spinal fusion. Spinal instability due to ASD may contribute to the development of spinal tumoral calcinosis, and surgical decompression and stabilization appear to be effective treatment options.

Indexed as

adjacent segment degenerationmyelopathyposterior decompression and fixationthoracolumbar spinetumoral calcinosis

Identifiers

PMID40166507
PMCPMC11955284

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.