Evidence map›Paper›PMID 40166417›Full record

ReviewBiomedical reports2025

Effects of fructose consumption during pregnancy in murine models (Review).

Ana Luisa Urrego Arredondo, Cristian David Moreno Urrutia, Juan David Gonzalez Calderon, Johanna Andrea Gutiérrez Vargas

Abstract readReview
In one paragraph

Review in Biomedical reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana Luisa Urrego ArredondoUniversity Institution Colegio Mayor de Antioquia, Medellín, Antioquia 65-46, Colombia.
Cristian David Moreno UrrutiaUniversity Institution Colegio Mayor de Antioquia, Medellín, Antioquia 65-46, Colombia.
Juan David Gonzalez CalderonUniremington Biomedical Research Group, Faculty of Health Sciences, Remington University Corporation, Medellín, Antioquia 51-27, Colombia.
Johanna Andrea Gutiérrez VargasNeuroscience and Aging Group (GISAM), Faculty of Health Sciences, Remington University Corporation, Medellín, Antioquia 51-27, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After standardizing methods for industrial fructose production, this sugar has been intensively used as a food additive. The growing use of this sugar in food has coincided with increased metabolic disorders in recent decades, and it remains a widely used sweetener. The high ingestion of fructose has contributed to the increasing prevalence of numerous chronic health conditions. Fructose intake and its impact during pregnancy and lactation have drawn the attention of researchers. In the present review, the latest information on the effects of maternal diets rich in fructose on rat or mouse offspring was compiled. The findings suggest a generalized negative response to excess fructose, such as alterations in mitochondrial function, neuroinflammation, oxidative stress, reproductive health, placental and intrauterine effects, epigenetics, transcriptomics modifications and cognitive function impairment. This demonstrates that chronic maternal fructose consumption could deteriorate the offspring's health.

Indexed as

animal modelfetal developmentfructosemetabolismpregnancy

Identifiers

PMID40166417
PMCPMC11956150

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.