Evidence map›Paper›PMID 40166281›Full record

ArticlebioRxiv : the preprint server for biology2025

Optimal Neuromuscular Performance Requires Motor Neuron Phosphagen Kinases.

Karlis A Justs, Danielle V Latner Nee Riboul, Carlos D Oliva, Yosuf Arab, Gabriel G Bonassi, Olena Mahneva, Sarah Crill, Sergio Sempertegui, Paul A Kirchman, Yaouen Fily and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Danielle V Latner Nee Riboul
Carlos D Oliva
Yosuf Arab
Gabriel G BonassiORCID 0009-0002-7548-1980
Olena Mahneva
Sergio Sempertegui
Gregory T MacleodORCID 0000-0003-3782-6968

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphagen systems are crucial for muscle bioenergetics - rapidly regenerating ATP to support the high metabolic demands of intense musculoskeletal activity. However, their roles in motor neurons that drive muscle contraction have received little attention. Here, we knocked down expression of the primary phosphagen kinase [Arginine Kinase 1; ArgK1] in

Identifiers

PMID40166281
PMCPMC11956927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.