ArticlebioRxiv : the preprint server for biology2025
Secreted retropepsin-like enzymes are essential for stress tolerance and biofilm formation in
Justin D Lormand, Charles H Savelle, Jennifer K Teschler, Eva López, Richard H Little, Jacob G Malone, Fitnat H Yildiz, María J García-García, Holger Sondermann
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Justin D LormandCSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany.
Charles H SavelleCSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany.
Jennifer K TeschlerDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, California, USA.
Eva LópezCSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany.
Richard H LittleDepartment of Molecular Microbiology, John Innes Centre, Norwich, UK.
Jacob G MaloneDepartment of Molecular Microbiology, John Innes Centre, Norwich, UK.
Fitnat H YildizDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, California, USA.ORCID 0000-0002-6384-7167 María J García-GarcíaCSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany.
Holger SondermannCSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany.ORCID 0000-0003-2211-6234 Funding
User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI STEVEN E EALICK · 2018 to 2026
$34.2MTraining and OutreachP30GM124166 · NIGMS · CORNELL UNIVERSITY · PI RICHARD A. CERIONE · 2019 to 2026
$28.3MVibrio cholerae biofilms: structure, function, regulation and role in infectionR01AI114261 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2014 to 2024
$5.0MPixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0McdG Signaling and Adhesion Deployment During Biofilm InitiationR01AI168017 · NIAID · DARTMOUTH COLLEGE · PI George A. O'Toole · 2022 to 2026
$1.9MNIAID NIH HHS R01 AI114261NIAID NIH HHS R01 AI168017NIGMS NIH HHS P30 GM124165NIGMS NIH HHS P30 GM124166NIH HHS S10 OD021527
6 · The paper itselfAbstract
Proteases regulate important biological functions. Here we present the structural and functional characterization of three previously uncharacterized aspartic proteases in
Identifiers
PMID40166241
PMCPMC11957051
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