Evidence map›Paper›PMID 40166208›Full record

ArticlebioRxiv : the preprint server for biology2025

LetA defines a structurally distinct transporter family involved in lipid trafficking.

Cristina C Santarossa, Yupeng Li, Sara Yousef, Hale S Hasdemir, Carlos C Rodriguez, Max B Haase, Minkyung Baek, Nicolas Coudray, John G Pavek, Kimber N Focke and 8 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Cristina C SantarossaORCID 0000-0002-6036-7870
Yupeng Li
Sara Yousef
Carlos C Rodriguez
Max B Haase
Minkyung Baek
John G Pavek
Kimber N Focke
Annika L Silverberg
Carmelita Bautista
Johannes Yeh
Michael T Marty

Funding

Structure and function of the LetA lipid transport family across bacteria and eukaryotesK99GM157496 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI SANTAROSSA, CRISTINA · 2024 to 2025
$250k
NIGMS NIH HHS K99 GM157496
6 · The paper itself

Abstract

Membrane transport proteins translocate diverse cargos, ranging from small sugars to entire proteins, across cellular membranes. A few structurally distinct protein families have been described that account for most of the known membrane transport processes. However, many membrane proteins with predicted transporter functions remain uncharacterized. We determined the structure of

Identifiers

PMID40166208
PMCPMC11957124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.