Evidence map›Paper›PMID 40165884›Full record

ArticleInternational journal of particle therapy2025

Operational Improvement of a Proton Therapy System From Reduced Energy Layer Switching Time.

Mark E Artz, Hardev S Grewal, Yawei Zhang, Perry B Johnson, Mohammad Saki, Niek Schreuder, Eric D Brooks, Jiyeon Park

Abstract read
In one paragraph

Article in International journal of particle therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mark E ArtzDepartment of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida, USA.
Hardev S GrewalDepartment of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida, USA.
Yawei ZhangDepartment of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida, USA.
Perry B JohnsonDepartment of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida, USA.
Mohammad SakiDepartment of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida, USA.
Niek SchreuderLeo Cancer Care, Middleton, Wisconsin, USA.
Eric D BrooksPremier Radiation Oncology Associates, Clearwater, Florida, USA.
Jiyeon ParkDepartment of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study reports the potential operational improvement provided by reduced energy layer switching time and total beam delivery time of a 3-room IBA ProteusPLUS system. Materials and methods: Eight treatment fields, including various disease sites and a reference cube, were analyzed for energy layer switching time and total delivery time before and after an energy layer switching time upgrade. The upgraded beam delivery time estimated the total treatment capacity for a 12-h treatment day using a 3-room system with a single common cyclotron. The potential increase in revenue was estimated using Medicare reimbursement rates for proton therapy intermediate. Results: The average layer switching time was reduced from 6.33 to 1.86 s, reducing the average field delivery time from 240 to 113 s. Overall, the average energy layer switching time reduction was 70.6%, and the average total treatment field delivery time was reduced by 52.6%. Head and neck cancer fields experienced the greatest treatment time reduction of 59.5%, reducing from 236 to 95.5 s. The treatment field delivery time reduction allowed an increase from 60 to 127 patients per day, an increase of 112%. Conclusion: Reductions in energy layer switching time significantly decreased treatment field delivery time. Reduced treatment field delivery time may provide clinical benefits to patients through improved patient alignment and comfort. Increased treatment capacity could also improve patient access to proton therapy for disease sites that may experience clinical benefits, such as head and neck cancer.

Indexed as

Energy layer switching timeProton beam delivery timeProton TherapyTreatment capacity improvement

Identifiers

PMID40165884
PMCPMC11957529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.