Evidence map›Paper›PMID 40165510›Full record

ArticleAlcohol, clinical & experimental research2025

One month follow-up outcomes of a transdermal alcohol concentration-based contingency management intervention to reduce heavy drinking among driving while intoxicated arrestees.

Nathalie Hill-Kapturczak, Richard J Lamb, John D Roache, Tae-Joon Moon, Yuanyuan Liang, Donald M Dougherty

Abstract read
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Article in Alcohol, clinical & experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nathalie Hill-KapturczakDepartment of Psychiatry & Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-9736-8885
Richard J LambDepartment of Psychiatry & Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0001-6644-768X
John D RoacheDepartment of Psychiatry & Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-7010-8119
Tae-Joon MoonDepartment of Psychiatry & Behavioral Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-2941-7323
Yuanyuan LiangDepartment of Epidemiology and Public Health, University of Maryland, Baltimore, Baltimore, Maryland, USA.
Donald M DoughertyDepartment of Psychology, University of North Texas, Denton, Texas, USA.

Funding

Leveraging Transdermal Alcohol Monitoring to Reduce Drinking among DWI DefendantsR01AA014988 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DOUGHERTY, DONALD M, HILL-KAPTURCZAK, NATHALIE · 2005 to 2021
$8.6M
Phosphatidylethanol and Other Ethanol Consumption MarkersR01AA022361 · NIAAA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Donald M Dougherty, Nathalie Hill-Kapturczak · 2013 to 2026
$3.5M
Assessing the Clinical and Cost-Effectiveness of a Virtual PEth-based Contingency Management for Adults with AUDR01AA031013 · NIAAA · WASHINGTON STATE UNIVERSITY · PI Nathalie Hill-Kapturczak, Michael G McDonell · 2023 to 2026
$2.8M
NIAAA NIH HHS R01 AA014988NIAAA NIH HHS R01AA014988NIAAA NIH HHS R01 AA022361NIAAA NIH HHS R01 AA031013NIAAA NIH HHS R01AA031013
6 · The paper itself

Abstract

backgroundHigh rates of driving while intoxicated persist, and recidivism is common. Recently, we demonstrated that 8 weeks of transdermal alcohol concentration (TAC)-based contingency management (CM) reduced heavy drinking (≥5 [men] or ≥4 [women] standard drinks) in 145 DWI arrestees under pretrial supervision. Here, we report 1-month (postintervention) follow-up outcomes for a subgroup of participants who were not Mandated to wear transdermal alcohol monitors.

methodsAfter the intervention, Non-Mandated participants (n = 100, 69%) returned for a 1-month follow-up visit and self-reported drinking during the previous month. Also, a fingerstick blood sample was used to measure the alcohol use biomarker phosphatidylethanol (PEth). PEth was measured by HPLC-MS/MS, with levels <20 ng/mL indicating low or no drinking. Multiple logistic regression models compared drinking outcomes (≤1 drinking day or ≤1 heavy drinking day) between the CM and Control groups (controlling for age, sex, White/non-White and drinking frequency prior to study entry).

resultsAnalyses showed that CM group participants were more likely to self-report ≤1 day of any drinking than those in the Control group (OR = 3.07, p = 0.03) and more likely to have ≤1 heavy drinking (OR = 4.13, p = 0.04). PEth results were consistent with the self-report, even though a nonsignificant trend toward a greater likelihood of having PEth levels <20 ng/mL was observed in the CM compared with the control group (OR = 2.29, p = 0.11).

conclusionsOutcomes observed after an 8-week TAC-based CM intervention appeared to persist for 1 month after a TAC-based CM intervention. Participants in the CM intervention group were more likely to have fewer drinking days and fewer heavy drinking days, as evidenced by self-reported drinking that was consistent with PEth levels <20 ng/mL.

Indexed as

Alcohol DrinkingAlcoholic IntoxicationAutomobile DrivingDriving Under the InfluenceEthanolAdministration, CutaneousAdultBiomarkersFemaleFollow-Up StudiesGlycerophospholipidsHumansMaleMiddle AgedTreatment OutcomeYoung AdultBiomarkersEthanolGlycerophospholipidsphosphatidylethanolalcoholbehavioral interventioncontingency managementdriving while intoxicatedphosphatidylethanoltransdermal alcohol concentration

Identifiers

PMID40165510
PMCPMC12097931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.