Evidence map›Paper›PMID 40165457›Full record

ArticleTransfusion2025

Use of non-qualifying umbilical cord blood units to support research and quality assurance by the Canadian Blood Services Cord Blood Bank.

David S Allan, Matthew D Seftel, An Duong, Harinad Maganti, Kathy Ganz, Nicholas Dibdin, Meagan Green, Jennifer Laycock, Subh Sarkar, Charlene Ropp and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transfusion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David S AllanStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0003-3261-8289
Matthew D SeftelStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
An DuongCancer Research Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Harinad MagantiStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Kathy GanzStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Nicholas DibdinStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Meagan GreenStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Jennifer LaycockStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Subh SarkarStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Charlene RoppStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Tanya PetraszkoStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.
Jelena L HolovatiStem Cells, Canadian Blood Services, Ottawa, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUmbilical cord blood units collected by Canadian Blood Services for public banking at selected collection hospitals may not meet stringent criteria for release to the bank's inventory and can be used to support research. The Cord Blood for Research Program (CB4RP) was established when the CBS bank was established, but the breadth of research activity supported by the CB4RP has not been previously described.

methodsRecords of projects and units requested to support research were reviewed and summarized from September 2014 to October 2024.

resultsA total of 34 projects have been supported by the CB4RP, with a total of 2901 units requested (85.4 units per project, range 6-540). To date, 1505 fresh units and 28 frozen units have been shipped to researchers. Areas of research supported by the CB4RP include hematopoietic cell transplant research, regenerative therapy, immunology research, cancer research, transfusion research, and other categories.

conclusionDistributing non-qualifying cord blood units for research leverages the public investments implicated in establishing the CBS CBB and supports the development of expertise across a broad range of research areas.

Indexed as

Biomedical ResearchBlood BanksFetal BloodQuality Assurance, Health CareBlood BankingCanadaHumansbankingcancerimmunologyregenerative therapyresearchtransfusiontransplantationumbilical cord blood

Identifiers

PMID40165457
PMCPMC12088300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.