Trial reportBMC psychology2025
Psychometric properties of the Brief Mishel Uncertainty in illness scales for patients with advanced cancer and their family caregivers.
Trial report in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Article
- Development and Validation of a Machine Learning-Based Prediction Model for Illness Uncertainty in Patients with Malignant Tumors.Healthcare (Basel, Switzerland) · 2026Article
- The Uncertainty in Illness Questionnaire (UIQ): development and validation of a clinically oriented measure for patients and caregivers.Health and quality of life outcomes · 2026Article
- A nurse-led cross-sectional latent profile analysis of fear of cancer recurrence in patients with non-muscle-invasive bladder cancer.Medicine · 2026Article
- The relationship between illness uncertainty and preoperative anxiety in surgical patients: the moderating role of mental health literacy.Frontiers in psychology · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThis study comprehensively examined the psychometric properties of the Brief Mishel Uncertainty in Illness Scale for patients (MUIS-P) managing advanced cancer and their caregivers (MUIS-Cg).
methodsThe MUIS-P and MUIS-Cg scales were developed based on the Mishel Uncertainty in Illness Scale-Adult. We conducted a secondary analysis to test the acceptability, factor structure, reliability, and validity of the brief uncertainty scales for patients with advanced cancer (N = 484) and their caregivers (N = 484) using data from a randomized clinical trial.
resultsThe 9-item MUIS-P and MUIS-Cg show goodness of fit for a two-factor structure (unpredictability and ambiguity) with adequate to acceptable internal consistency (Cronbach's alpha 0.66-0.78 for patients and 0.70-0.72 for caregivers and McDonald's omega 0.72-0.84 for patients and 0.76-0.79 for caregivers). The MUIS-P and MUIS-Cg scores correlated with negative appraisals of illness/caregiving, hopelessness, and avoidant coping, demonstrating convergent validity. The discriminant validity of the MUIS-P and MUIS-Cg was evidenced by their significant correlations with self-efficacy and active coping. The baseline MUIS-P and MUIS-Cg scores were significantly associated with quality of life, hopelessness, depression, distress, and avoidant coping at the 3-month follow-up, indicating their strong predictive validity.
conclusionThis study comprehensively evaluated the psychometric properties of the MUIS-P and MUIS-Cg, laying a foundation for their use in research and clinical practice among patients and caregivers managing demanding symptoms and care.
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