ArticleBMC public health2025
Global, regional, and national burden of thyroid cancer in young people aged 10-24 years from 1990 to 2021: an analysis based on the Global Burden of Disease Study 2021.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Global, regional, and national burden and quality of care index of five head and neck cancers: a 32-year longitudinal analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Spatial and temporal distribution of thyroid cancer incidence in China: An ecological study based on a national registry.PloS one · 2026Article
- Sex chromosomes/hormones and the tumor microenvironment of non-reproductive cancers.Frontiers in immunology · 2025Review
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7 authors.
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Abstract
backgroundThe burden of thyroid cancer (TC) among young people aged 10-24 years has not been systematically studied to date. This study aims to analyze the burden of TC among young people aged 10-24 years globally, regionally, and nationally from 1990 to 2021.
methodsWe collected data on the incidence, mortality, and disability-adjusted life years (DALYs) rates for TC among young people aged 10-24 years from 1990 to 2021 using the Global Burden of Disease (GBD) 2021. Joinpoint regression analysis, frontier analysis, and health inequality analysis were employed to examine the variations and changes in TC burden among young people aged 10-24 years across different countries and regions.
resultsFrom 1990 to 2021, the global burden of TC among young people has increased from 2.726 per 100,000 people [95% Uncertainty Interval (UI) 2.38-3.181] to 2.956 per 100,000 people (95% UI: 2.339-3.922), with an Average Annual Percent Change (AAPC) of 0.258 (95% Confidence Interval (CI): 0.138-0.378). The highest incidence rates were observed in Saudi Arabia, Taiwan (China), and Vietnam, while the highest mortality rates were in India, China, and Bangladesh. Frontier analysis revealed that the largest disparities in effective differences were found in the Netherlands, Germany, Canada, the United States of America, and Guinea-Bissau. The Slope Index of Inequality (SII) for DALYs increased slightly from -0.15 in 1990 to -1.3 in 2021.
conclusionsOver the past three decades, the burden of TC has increased globally among young people, particularly in poorer countries and regions. This study highlights the importance of formulating public health policies tailored to the specific circumstances of different countries and regions aimed at reducing the TC burden among young people.
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