Evidence map›Paper›PMID 40165158›Full record

SynthesisBMC nephrology2025

Safety and efficacy of transcatheter arterial embolization in renal angiomyolipomas: a systematic review and meta-analysis.

Shahid Miangul, Karen Smayra, Liranne Bitton, Reem B Zalloum, Nathanael Q E Yap, Baraa Saad, Rangish Yuvaraj, Marios Alogakos, Hayato Nakanishi, Christian A Than and 1 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Interpreting Embolic Agent Comparisons in Renal Angiomyolipoma Embolisation.Journal of medical imaging and radiation oncology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shahid MiangulSt George's University of London, London, SW17 0RE, UK.
Karen SmayraSt George's University of London, London, SW17 0RE, UK.
Liranne BittonUniversity of Nicosia Medical School, University of Nicosia, Nicosia, 2417, Cyprus.
Reem B ZalloumCollege of Liberal Arts and Sciences, University of Illinois at Chicago (UIC), Chicago, 60607, USA.
Nathanael Q E YapSt George's University of London, London, SW17 0RE, UK.
Baraa SaadSt George's University of London, London, SW17 0RE, UK.
Rangish YuvarajBaylor Scott & White Allsaints Medical Center, Fort Worth, Texas, TX, 76104, USA.
Marios AlogakosSt George's University of London, London, SW17 0RE, UK.
Hayato NakanishiSt George's University of London, London, SW17 0RE, UK.
Christian A ThanSchool of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, 4072, Australia. cat69@cam.ac.uk.
Aneeta ParthipunInterventional Radiology, Guy's, St Thomas' and Evelina Children's Hospital, London, SE17EH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTranscatheter arterial embolization (TAE) is increasingly utilized in the management of renal angiomyolipomas (AML). However, the growth in its application has not been matched by a proportional increase in the level of evidence validating its safety and efficacy. This meta-analysis aims to evaluate TAE in managing renal AMLs by examining the effects of tumour size reduction and technical success.

methodsA literature search of several databases was conducted from inception to July 2023. Eligible studies reported adult patients (≥ 18 years old) who underwent TAE for renal AML. The pooled proportions were analyzed using a random-effects model. This review was registered in PROSPERO (CRD42023441331).

resultsA total of 32 studies comprising 1087 patients were included. The average preoperative tumour size across renal AMLs was 8.79 cm (95% CI: 7.64, 9.93; I

conclusionThis meta-analysis provides insights into the efficacy of TAE for renal AMLs, emphasizing notable tumour size reduction and a high technical success rate for selected patients. Despite identified biases, the findings support TAE as a valuable intervention, warranting further research to refine safety profiles and optimize patient outcomes.

Indexed as

AngiomyolipomaEmbolization, TherapeuticKidney NeoplasmsHumansTreatment OutcomeTumor BurdenMeta-analysisRenal angiomyolipomaTechnical successTranscatheter arterial embolizationTumour size reduction

Identifiers

PMID40165158
PMCPMC11956202

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.