SynthesisBMC public health2025
The odds of developing asthma and wheeze among children and adolescents exposed to particulate matter: asystematic review and meta-analysis.
Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Indoor Microbiome: Sampling, Analysis and Emerging Trends.Environmental microbiology reports · 2026Pooled it
- Long-term exposure to ambient particulate matter and its association with Alzheimer's disease: influencing factors and a systematic review with meta-analysis.Frontiers in public health · 2026Pooled it
- Chemical constituents of PMEuropean journal of pediatrics · 2025Pooled it
- The Modern Environment and Childhood Asthma: The Role of Air Pollution and Heavy Metal Exposure.Current allergy and asthma reports · 2026Review
- Perspectives and Needs of Caregivers in Protecting Their Child With Asthma From Wildfire Smoke.Pediatric pulmonology · 2026Article
- Development of the Respiratory System During Adolescence.Advances in experimental medicine and biology · 2026Review
- Indoor air pollution in kindergartens is a stronger predictor of preschool wheezing than household pets and passive smoking.Frontiers in public health · 2026Article
- The Interlinkages Between Ambient Temperature and Air Pollution in Exacerbating Childhood Asthma: A Time Series Study in Cape Town, South Africa.Children (Basel, Switzerland) · 2025Article
- Effect of particulate matter pollution on the global burden of lower respiratory infections in children and adolescents, 1990-2021: a systematic analysis from the global burden of disease study 2021.BMC public health · 2025Article
- Xenobiotic Toxicants and Particulate Matter: Effects, Mechanisms, Impacts on Human Health, and Mitigation Strategies.Journal of xenobiotics · 2025Review
- Evaluating the Impact of Air Quality on Pediatric Asthma-Related Emergency Room Visits in the Eastern Province of Saudi Arabia.Journal of clinical medicine · 2025Article
- Developing a community-prioritized research agenda on primary care strategies for minimizing the health impacts of heat and poor air quality events: protocol.Frontiers in climate · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure to air pollution specifically particulate matter causes significant health risk to children which increases their susceptibility to respiratory diseases.
objectivesThis review aimed to pool the association between particulate matter exposure and childhood asthma and wheeze among children and adolescents.
methodsThis review included observational study articles retrieved from electronic data bases such as PubMed, Google Scholar, Hinari, Science Direct, and Semantic Scholar from 1996 to June 17, 2024. Data were extracted and analyzed using Microsoft Excel 16 and STATA version 17, respectively. Joanna Briggs Institute evaluation criteria and I
resultsFourty seven studies with a total of 417,874 of children and adolescents met the inclusion criteria. The pooled odd ratio (OR) of the association between Particulate Matter with a diameter of 10 micrometers or less (PM10) and Particulate Matter with a diameter of 2.5 micrometers or less (PM2.5) with asthma were 1.04 (95% CI: 1.03-1.06, p < 0.001) with significant extreme heterogeneity (I² = 82.7%, p < 0.001) and 1.05 (95% CI 1.04-1.07, p < 0.001) with high heterogeneity (I² = 80.6%, p < 0.001) among the included studies, respectively. The overall pooled estimate indicates a statistically significant association between PM10 and wheeze, with OR of 1.06 (95% CI: 1.05, 1.07) and moderate heterogeneity among included studies (I²=57.5%, p < 0.007) where as more association was observed between PM2.5 and wheeze with OR of 1.15. (95% CI: 1.10, 1.20) with an (I² =72.8%, p < 0.001).
conclusionThe findings of this systematic review and meta-analysis demonstrated a statistically significant association between exposure to both PM10 and PM2.5 and the occurrence of asthma and wheezing in children and adolescents. Both PM10 and PM2.5 are associated with increased odds of asthma and wheezing, with PM2.5 showing a stronger relationship. The significant levels of heterogeneity observed suggest variations across studies, which may be due to differences in study designs, exposure level and outcome measurement types. These findings indicate the need for strategies to reduce particle air pollution to mitigate its adverse effects on children's respiratory health.
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