ArticleBMC pediatrics2025
Evaluating tidal volume stability in extremely preterm infants on high-frequency oscillatory ventilation with volume guarantee.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh Frequency Oscillatory Ventilation (HFOV) combined with volume guarantee (HFOV-VG) represents an innovative ventilation mode designed for managing respiratory failure in neonates. This study aimed to assess the stability of High Frequency tidal volume (VThf) in extremely preterm infants ventilated on HFOV with VG during the first 48 h of life. Additional objectives included examining the correlations between VThf, Diffusion Coefficient of Carbon Dioxide (DCO
methodsThis retrospective, single-center study included 22 extremely preterm infants treated with HFOV-VG as the primary mode of ventilation at King Abdulaziz Medical City. Data were collected directly from the ventilator every minute for the first 48 h of life. Blood gases were analyzed every 4-6 h to maintain normocapnia (PCO
resultsTwenty-two infants had a median gestational age of 26.5 weeks (IQR 24-28) and a median birth weight of 830 g (IQR 600-1300). The median set VThf per kilogram was 2.2 mL/kg [IQR 2,2.6], which was consistent with the measured VThf. Significant correlations were observed between weight-corrected DCO
conclusionsHFOV-VG effectively stabilized VThf in extremely preterm infants with fluctuations in amplitude, providing consistent ventilation support during the early critical period. The weight-corrected DCO
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