Evidence map›Paper›PMID 40165102›Full record

ArticleBMC infectious diseases2025

Capillary lactate as a prognostic marker in sepsis: correlation with venous lactate and prediction of outcomes.

Philip A Joseph, Dinul Doluweera, Amalka Chandraratne, Branavan Balasubramaniam, Varuna Abeyratne, Saman P Hewa, Roshan Rambukwella, Kamani P Wanigasuriya, Jegarajah Indrakumar, Nilanka Perera

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Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Philip A JosephUniversity Medical Unit, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
Dinul DoluweeraDepartment of Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Amalka ChandraratneDepartment of Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Branavan BalasubramaniamUniversity Medical Unit, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
Varuna AbeyratneDepartment of Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Saman P HewaDepartment of Chemical Pathology, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
Roshan RambukwellaProvincial Department of Health Services, Central Province, Kundasale, Sri Lanka.
Kamani P WanigasuriyaDepartment of Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Jegarajah IndrakumarDepartment of Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Nilanka PereraDepartment of Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka. nilanka@sjp.ac.lk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVenous lactate (VL) measured by a blood‒gas analyser is not widely available despite its importance in the management of sepsis. Capillary lactate (CL) measured via a hand-held lactate analyser is a feasible and less expensive option. The aim of this study was to determine the correlation between CL and VL in sepsis patients at 0 h (t

methodsA descriptive study was conducted recruiting all patients with suspected sepsis (qSOFA ≥ 2 with evidence of infection) admitted to a tertiary care hospital in Sri Lanka between March and June 2022. "Lactate-plus", a hand-held lactate analyser, was used to measure CL and VL at t

resultsThere were 102 patients with suspected sepsis and a median age of 71.5 (interquartile range: 62-77) years were recruited. Majority were females (n = 52, 51%). Majority of the source of infection was pulmonary (n = 57, 55.9%) and urological (n = 19, 18.6%). Paired CL and VL values significantly correlated at both t

conclusionsCL measured by a lactate meter correlates well with VL and effectively predicts sepsis outcomes. A CL cut-off ≥ 3.5 mmol/L at admission increases the risk of mortality, vasopressor requirement and ICU admission, making CL a useful tool for risk assessment in sepsis.

Indexed as

CapillariesLactic AcidSepsisAgedBiomarkersFemaleHumansMaleMiddle AgedPilot ProjectsPrognosisROC CurveSri LankaVeinsBiomarkersLactic AcidBiomarkerCapillary lactateLactateLactate clearanceMortality predictionPoint-of-care testingSepsis

Identifiers

PMID40165102
PMCPMC11956252

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.