Evidence map›Paper›PMID 40165065›Full record

ArticleBMC bioinformatics2025

optRF: Optimising random forest stability by determining the optimal number of trees.

Thomas M Lange, Mehmet Gültas, Armin O Schmitt, Felix Heinrich

Abstract read
In one paragraph

Article in BMC bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas M LangeBreeding Informatics Group, Georg-August University, Margarethe Von Wrangell-Weg 7, 37075, Göttingen, Germany. thomas.lange@uni-goettingen.de.ORCID http://orcid.org/0000-0003-4351-7950
Mehmet GültasFaculty of Agriculture, South Westphalia University of Applied Sciences, Lübecker Ring 2, 59494, Soest, Germany.ORCID http://orcid.org/0000-0003-3297-3192
Armin O SchmittBreeding Informatics Group, Georg-August University, Margarethe Von Wrangell-Weg 7, 37075, Göttingen, Germany.ORCID http://orcid.org/0000-0002-4910-9467
Felix HeinrichBreeding Informatics Group, Georg-August University, Margarethe Von Wrangell-Weg 7, 37075, Göttingen, Germany.ORCID http://orcid.org/0000-0002-6093-8522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Machine learning is frequently used to make decisions based on big data. Among these techniques, random forest is particularly prominent. Although random forest is known to have many advantages, one aspect that is often overseen is that it is a non-deterministic method that can produce different models using the same input data. This can have severe consequences on decision-making processes. In this study, we introduce a method to quantify the impact of non-determinism on predictions, variable importance estimates, and decisions based on the predictions or variable importance estimates. Our findings demonstrate that increasing the number of trees in random forests enhances the stability in a non-linear way while computation time increases linearly. Consequently, we conclude that there exists an optimal number of trees for any given data set that maximises the stability without unnecessarily increasing the computation time. Based on these findings, we have developed the R package optRF which models the relationship between the number of trees and the stability of random forest, providing recommendations for the optimal number of trees for any given data set.

Indexed as

Computational BiologyMachine LearningSoftwareAlgorithmsRandom ForestDecision-makingGenomic selectionMachine learningNon-determinismParameter optimisationRandom forestVariable selection

Identifiers

PMID40165065
PMCPMC11959736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.