Evidence map›Paper›PMID 40164929›Full record

Observational studyClinical neuroradiology2025

Cumulative Radiation Exposure Post Aneurysmal Subarachnoid Haemorrhage.

Shreepad H Asundi, Mark P Plummer, Krishnaswamy Sundararajan, Gerry O'Callaghan, Palash Kar, Alistair Jukes, Chris M Boyd, Weitong Chen, Chang Dong, Timothy Webber

Abstract readObservational Study
In one paragraph

Observational study in Clinical neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shreepad H AsundiDepartment of Intensive Care, Royal Adelaide Hospital, 5000, Adelaide, South Australia, Australia.
Mark P PlummerDepartment of Intensive Care, Royal Adelaide Hospital, 5000, Adelaide, South Australia, Australia.
Krishnaswamy SundararajanDepartment of Intensive Care, Royal Adelaide Hospital, 5000, Adelaide, South Australia, Australia.
Gerry O'CallaghanDepartment of Intensive Care, Royal Adelaide Hospital, 5000, Adelaide, South Australia, Australia.
Palash KarDepartment of Intensive Care, Royal Adelaide Hospital, 5000, Adelaide, South Australia, Australia.
Alistair JukesAdelaide Medical School, The University of Adelaide. Adelaide, South Australia 5000, Adelaide, Australia.
Chris M BoydMedical Physics & Radiation Safety, South Australia Medical Imaging, South Australia 5000, Adelaide, Australia.
Weitong ChenAustralian Institute for Machine Learning, The University of Adelaide, 5005, Adelaide, South Australia, Australia.
Chang DongSchool of computer and mathematical Sciences, The University of Adelaide, South Australia 5005, Adelaide, Australia.
Timothy WebberDepartment of Intensive Care, Royal Adelaide Hospital, 5000, Adelaide, South Australia, Australia. Timothy.webber@sa.gov.au.ORCID http://orcid.org/0000-0001-5748-3881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with aneurysmal subarachnoid haemorrhage (aSAH) often receive multiple radiation based diagnostic studies. Cumulative radiation exposure has been associated with long term health consequences from both dose dependent deterministic harm and increased risk of developing adverse events in a non-dose dependant manner i.e. stochastic harm.

objectiveThe objective was to calculate cumulative radiation exposure in the acute phase after aSAH. DESIGN, SETTING, PARTICIPANTS,

main outcome measuresSingle centre retrospective, observational study of consecutive adult patients admitted to the ICU for management of aSAH over five years. Organ and effective radiation doses were determined using institution specific conversion coefficients based on scanner radiation output metrics for all computed tomography imaging and fluoroscopy examinations. Calculated patient doses for the duration of the hospital admission were determined using National Cancer Institute radiation dosimetry tools.

resultsA total of 276 patients met the inclusion criteria; 180 females (65%), mean (SD) age 56 (13) years. There were 222 (80%) patients who survived to hospital discharge. The median [IQR] effective cumulative radiation dose was 17.7 [9.7-30.5] mSv. Twenty-one patients (8%) received an effective dose > 50 mSV consistent with potentially harmful ionising radiation exposure. In 162 patients (59%), the equivalent radiation dose to the lens of the eye exceeded the 500 mSv threshold for radiation induced damage.

conclusionSurvivors of aSAH are exposed to high levels of medical radiation. The eyes are particularly at risk with most patients exposed to levels known to induce lens damage. This highlights the importance of strategies to reduce incidental and cumulative medical radiation exposure in this population.

Indexed as

Radiation ExposureRadiation InjuriesSubarachnoid HemorrhageTomography, X-Ray ComputedAdultAgedFemaleFluoroscopyHumansMaleMiddle AgedRadiation DosageRetrospective StudiesIonising radiationLensNeurosurgerySubarachnoid haemorrhage

Identifiers

PMID40164929
PMCPMC12454507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.