Trial reportAnnals of internal medicine2025
Patient Navigation to Improve Colonoscopy Completion After an Abnormal Stool Test Result : A Randomized Controlled Trial.
Trial report in Annals of internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03925883 (Predicting and Addressing Colonoscopy in Safety Net Settings), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Predicting and Addressing Colonoscopy in Safety Net Settings
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Improving Diagnostic Colonoscopy Completion After Positive Stool-Based Screening in Health-Disparity Populations: A Systematic Review and Meta-analysis.Journal of general internal medicine · 2026Pooled it
- Time to Follow-Up Colonoscopy After Positive Fecal Immunochemical Test with Centralized Patient Navigation: A Randomized Clinical Trial.Journal of general internal medicine · 2026Trial
- Rates and Timing of Follow-up Colonoscopy After a Positive Stool-Based Test in an Integrated Health System.Journal of general internal medicine · 2026Article
- Factors Associated with Adherence to Recommended Colorectal Surveillance Intervals in Lynch Syndrome.Cancers · 2026Article
- Barriers to Timely Colonoscopy Completion Following Abnormal Fecal Immunochemical Test Results in a Safety-net System.Journal of general internal medicine · 2026Article
- Article
- Modeled Cost-Effectiveness of a Rideshare Program to Facilitate Colonoscopy Completion.JAMA network open · 2025Article
- Application of Patient Navigation in Colorectal Cancer Screening: A Scoping Review.Cancer management and research · 2025Review
- Difference-making factors for successful implementation of a multicomponent colorectal cancer screening program in rural clinics (SMARTER CRC).Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundPatient navigation is a recommended practice of the Guide to Community Preventive Services; little is known about whether it improves colonoscopy completion for adults who have received an abnormal stool test result.
objectiveTo determine whether patient navigation delivered to persons with an abnormal stool test result increased follow-up colonoscopy completion (primary) at 1 year.
designRandomized controlled trial. (ClinicalTrials.gov: NCT03925883).
settingA federally qualified health center ( PATIENTS: Persons aged 50 to 75 years with an abnormal fecal test result in the prior month.
interventionA 6-topic, telephone-based patient navigation program delivered by bilingual (English and Spanish) clinical staff. MEASUREMENTS: Receipt of follow-up colonoscopy at 1 year (primary); time to colonoscopy receipt (secondary); and program effectiveness by patient characteristics, including patients' probability of obtaining a colonoscopy without navigation, derived using health record data (secondary).
resultsOf 985 participants enrolled (mean age, 61 years [SD, 6.8]; 170 [18%] had a Spanish-language preference listed in the medical record), 967 were included in the primary intention-to-treat analysis (479 in patient navigation, 488 in usual care). Receipt of follow-up colonoscopy was higher in the patient navigation group than in the usual care group (55.1% vs. 42.1%; risk difference, 13.0 percentage points [95% CI, 6.5 to 19.4 percentage points]). The intervention effect was not moderated by patients' probability of obtaining a colonoscopy without navigation. LIMITATION: The study was primarily done during the height of the COVID-19 pandemic, which created additional barriers to colonoscopy at the health system and patient levels.
conclusionThese findings support the effectiveness of patient navigation for follow-up colonoscopy completion. PRIMARY FUNDING SOURCE: National Cancer Institute.
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Registered trials
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