Evidence map›Paper›PMID 40163853›Full record

ArticleJournal of medical Internet research2025

Ability of ChatGPT to Replace Doctors in Patient Education: Cross-Sectional Comparative Analysis of Inflammatory Bowel Disease.

Zelin Yan, Jingwen Liu, Yihong Fan, Shiyuan Lu, Dingting Xu, Yun Yang, Honggang Wang, Jie Mao, Hou-Chiang Tseng, Tao-Hsing Chang and 1 more

Abstract readComparative Study
In one paragraph

Article in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Zelin Yan *Zhejiang Provincial Key Laboratory of Gastrointestinal Diseases Pathophysiology, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.ORCID 0009-0005-3123-4875
Jingwen Liu *Center of Inflammatory Bowel Diseases, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0001-5179-1592
Yihong Fan *Zhejiang Provincial Key Laboratory of Gastrointestinal Diseases Pathophysiology, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.ORCID 0000-0001-9554-0541
Shiyuan LuCenter of Inflammatory Bowel Diseases, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-2825-8244
Dingting XuCenter of Inflammatory Bowel Diseases, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0001-8728-2378
Yun YangThe Clinical Medical College, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0009-0009-3323-7569
Honggang WangDepartment of Gastroenterology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, China.ORCID 0000-0003-4761-0407
Jie MaoThe Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.ORCID 0009-0006-9597-1249
Hou-Chiang TsengGraduate Institute of Digital Learning and Education, National Taiwan University of Science and Technology, Taipei, Taiwan.ORCID 0000-0001-5249-7280
Tao-Hsing ChangDepartment of Computer Science and Information Engineering, National Kaohsiung University of Science and Technology, Kaohsiung, Taiwan.ORCID 0000-0003-4390-5021
Yan ChenCenter of Inflammatory Bowel Diseases, Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0003-3457-2560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough large language models (LLMs) such as ChatGPT show promise for providing specialized information, their quality requires further evaluation. This is especially true considering that these models are trained on internet text and the quality of health-related information available online varies widely.

objectiveThe aim of this study was to evaluate the performance of ChatGPT in the context of patient education for individuals with chronic diseases, comparing it with that of industry experts to elucidate its strengths and limitations.

methodsThis evaluation was conducted in September 2023 by analyzing the responses of ChatGPT and specialist doctors to questions posed by patients with inflammatory bowel disease (IBD). We compared their performance in terms of subjective accuracy, empathy, completeness, and overall quality, as well as readability to support objective analysis.

resultsIn a series of 1578 binary choice assessments, ChatGPT was preferred in 48.4% (95% CI 45.9%-50.9%) of instances. There were 12 instances where ChatGPT's responses were unanimously preferred by all evaluators, compared with 17 instances for specialist doctors. In terms of overall quality, there was no significant difference between the responses of ChatGPT (3.98, 95% CI 3.93-4.02) and those of specialist doctors (3.95, 95% CI 3.90-4.00; t

conclusionsChatGPT demonstrated more stable performance across various dimensions. Its output of health information content is more structurally sound, addressing the issue of variability in the information from individual specialist doctors. ChatGPT's performance highlights its potential as an auxiliary tool for health information, despite limitations such as artificial intelligence hallucinations. It is recommended that patients be involved in the creation and evaluation of health information to enhance the quality and relevance of the information.

Indexed as

Inflammatory Bowel DiseasesInternetPatient Education as TopicPhysiciansAdultCross-Sectional StudiesFemaleGenerative Artificial IntelligenceHumansMaleMiddle AgedSurveys and QuestionnairesAI-assistedartificial intelligenceChatGPTconversational agentsdisease managementinflammatory bowel diseaseonline health informationpatient communitiespatient educationreadabilitysocial media

Identifiers

PMID40163853
PMCPMC11997527

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.