Evidence map›Paper›PMID 40163737›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Peto's paradox revisited (revisited, revisited, revisited, and revisited yet again).

Vincent J Lynch

Abstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Evolution of the highest fidelity DNA replication systems.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Reply to Compton et al.: Another paradoxical misunderstanding.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Reply to Compton et al.: Paradoxical misunderstanding.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Vincent J LynchDepartment of Biological Sciences, University at Buffalo, State University at New York, Buffalo, NY 14260.ORCID 0000-0001-5311-3824

Funding

Exploring the cellular mechanisms of enhanced lifespan in batsR21AG078784 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LYNCH, VINCENT J., SEARS, KAREN E · 2022 to 2023
$447k
NIA NIH HHS R21 AG078784
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40163737
PMCPMC12002202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.