Evidence map›Paper›PMID 40163471›Full record

ReviewPLoS pathogens2025

Advances in the dissection of Anopheles-Plasmodium interactions.

Sally A Saab, Victor Cardoso-Jaime, Mary Kefi, George Dimopoulos

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Distinct Genetic Footprint of Adaptation Observed WithinResearch and reports in tropical medicine · 2026
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sally A SaabW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States America.
Victor Cardoso-JaimeW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States America.
Mary KefiW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States America.
George DimopoulosW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States America.ORCID 0000-0001-6755-8111

Funding

Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of miceR01AI158615 · NIAID · YALE UNIVERSITY · PI DIMOPOULOS, GEORGE, FIKRIG, EROL · 2021 to 2025
$4.1M
Impact of gene-drive systems for population modification on malaria vector mosquitoesR01AI170692 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI DIMOPOULOS, GEORGE, JAMES, ANTHONY A. · 2023 to 2025
$3.2M
NIAID NIH HHS R01 AI158615NIAID NIH HHS R01 AI170692
6 · The paper itself

Abstract

Malaria is a life-threatening mosquito-borne disease caused by the Plasmodium parasite, responsible for more than half a million deaths annually and principally involving children. The successful transmission of malaria by Anopheles mosquitoes relies on complex successive interactions between the parasite and various mosquito organs, host factors, and restriction factors. This review summarizes our current understanding of the mechanisms regulating Plasmodium infection of the mosquito vector at successive plasmodial developmental stages and highlights potential transmission-blocking targets and strategies.

Indexed as

AnophelesHost-Parasite InteractionsMalariaMosquito VectorsPlasmodiumAnimalsHumans

Identifiers

PMID40163471
PMCPMC11957333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.