Evidence map›Paper›PMID 40163431›Full record

ArticlePloS one2025

When effort pays off: An experimental investigation into action orientation and anxiety as buffering factors between anhedonia and reward motivation.

Michael R Gallagher, Amanda C Collins, Samantha L Anduze, E Samuel Winer

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Not Feeling It: Modifiable Correlates of Anhedonia.Behavioral sciences (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael R GallagherDepartment of Psychology, Mississippi State University, Mississippi State, Mississippi, United States of America.ORCID 0000-0002-4239-7750
Amanda C CollinsDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Samantha L AnduzeDepartment of Psychology, The New School for Social Research, New York, New York, United States of America.
E Samuel WinerDepartment of Psychology, The New School for Social Research, New York, New York, United States of America.

Funding

Reward Devaluation, Positive Valence Systems Disturbance, and ImpairmentR15MH101573 · NIMH · NEW SCHOOL UNIVERSITY · PI E. Samuel Winer · 2014 to 2026
$1.8M
NIMH NIH HHS R15 MH101573
6 · The paper itself

Abstract

Reward motivation, a construct tied to depression, has been studied using the Effort-Expenditure for Rewards Task (EEfRT). Prior work indicates that anhedonia can reduce reward motivation on the EEfRT, as those with higher levels of anhedonia tend to engage in low reward tasks that require less effort as opposed to expending higher levels of effort to obtain a larger reward. Action orientation has shown to act as a buffer at low levels of anhedonia, but this effect has not been seen at high levels of anhedonia. The current study examined if these findings replicated without a stress manipulation and explored the interaction between anxiety and anhedonia in predicting persistence on the EEfRT using two moderation models. Participants (N =  101) with varying levels of depressive symptoms took part in the study. The first model examined the effects of anhedonia and action orientation on reward motivation. The second model investigated the influence of anhedonia and anxiety on reward motivation. Findings revealed that higher levels of anhedonia were significantly associated with lower reward motivation in both models. Additionally, the interaction between anhedonia and action orientation on reward motivation was significant. Trend analyses revealed that, at low levels of anhedonia, participants generally made more high-effort/high-reward choices or were willing to exude more effort for the possibility of obtaining a greater reward. However, as anhedonia increased, individuals with higher levels of action orientation exhibited greater effort as opposed to those with lower action orientation. The findings indicate that anhedonia has a strong impact on limiting reward motivation. However, high levels of action orientation can mitigate the negative influence of anhedonia on reward motivation.

Indexed as

AnhedoniaAnxietyMotivationRewardAdolescentAdultDepressionFemaleHumansMaleYoung Adult

Identifiers

PMID40163431
PMCPMC11957302

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.