Evidence map›Paper›PMID 40163376›Full record

ArticleeLife2025

Interdependence between SEB-3 receptor and NLP-49 peptides shifts across predator-induced defensive behavioral modes in

Kathleen T Quach, Gillian A Hughes, Sreekanth H Chalasani

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. eLife · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathleen T QuachMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, United States.ORCID https://orcid.org/0000-0001-8498-1464
Gillian A HughesMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, United States.
Sreekanth H ChalasaniMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, United States.ORCID https://orcid.org/0000-0003-2522-8338

Funding

Dissecting molecular elements of threat behaviorR01MH113905 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CHALASANI, SREEKANTH H. · 2017 to 2021
$2.4M
NIMH NIH HHS R01 MH113905NIMH NIH HHS R01MH113905
6 · The paper itself

Abstract

Prey must balance predator avoidance with feeding, a central dilemma in prey refuge theory. Additionally, prey must assess predatory imminence-how close threats are in space and time. Predatory imminence theory classifies defensive behaviors into three defense modes: pre-encounter, post-encounter, and circa-strike, corresponding to increasing levels of threat--suspecting, detecting, and contacting a predator. Although predatory risk often varies in spatial distribution and imminence, how these factors intersect to influence defensive behaviors is poorly understood. Integrating these factors into a naturalistic environment enables comprehensive analysis of multiple defense modes in consistent conditions. Here, we combine prey refuge and predatory imminence theories to develop a model system of nematode defensive behaviors, with

Indexed as

Behavior, AnimalCaenorhabditis elegansCaenorhabditis elegans ProteinsNeuropeptidesPredatory BehaviorAnimalsCaenorhabditis elegans ProteinsNeuropeptidesC. elegansdefensive behaviorsecologyneuroscienceNLP-49 peptidesP. pacificuspredatorSEB-3 receptor

Identifiers

PMID40163376
PMCPMC11957542

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.