Evidence map›Paper›PMID 40163286›Full record

ArticleJournal of ultrasound2025

The effect of repetitive exercise on tensile changes in the infraspinatus muscle evaluated with ultrasound elastography.

Austin T Coale, Stephanie C Pittman, Coby B Dorsey, Farhan Chowdry, David J Berkoff

Abstract read
In one paragraph

Article in Journal of ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Austin T CoaleUniversity of North Carolina School of Medicine, 321 S Columbia St, Chapel Hill, NC, 27599, USA. austin_coale@med.unc.edu.ORCID http://orcid.org/0000-0002-7488-4537
Stephanie C PittmanDepartment of Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, 3471 Fifth Ave, Pittsburgh, PA, 15213, USA.
Coby B DorseyUniversity of North Carolina School of Medicine, 321 S Columbia St, Chapel Hill, NC, 27599, USA.
Farhan ChowdryUniversity of North Carolina School of Medicine, 321 S Columbia St, Chapel Hill, NC, 27599, USA.
David J BerkoffDepartment of Orthopaedics and Sports Medicine, University of North Carolina, 130 Mason Farm Rd Suite 3147, Chapel Hill, NC, 27514, USA.

Funding

SHORT-TERM RESEARCH TRAININGT35DK007386 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Evan Samuel Dellon · 1986 to 2026
$4.1M
NIDDK NIH HHS T35 DK007386NIDDK NIH HHS T35-DK007386
6 · The paper itself

Abstract

backgroundThe ability to identify muscle strain accurately is a critical aspect in managing exercise-induced muscle damage. Using differences in muscle stiffness as a proxy for muscle damage and recovery can better inform the decision to continue exercise versus pursue recovery. HYPOTHESIS/PURPOSE: To identify changes in rotator cuff stiffness after a single bout of exercise as measured by ultrasound elastography. STUDY

design10 healthy subjects, average age of 23.7, were enrolled in this prospective interventional trial. Each subject had a baseline scan then completed a standardized exercise program followed by another scan and daily evaluations until the results returned to within 10% of baseline.

methodsElastography measurements were collected around the infraspinatus tendon, and the deltoid was used as a baseline standard. STATISTICAL ANALYSIS USED: Summary statistics, t-test, and regression analysis were completed for the data.

resultsAverage strain was 0.5 at baseline, 0.7 immediately post-exercise, 0.6 on follow-up day 1, and 0.4 on follow-up day 2. There were statically significant differences between every timepoint. baseline-post 0.24, (p < 0.0001), post-day1 (decrease of 0.14, p < 0.0001), day1-day2 (decrease of 0.15, p < 0.0001), and BL-day2 (decrease of 0.05, p < 0.005).

conclusionsThese results demonstrate that the infraspinatus muscle stiffness increases immediately after exercise and takes up to 48 h to return to within 10% of baseline. We also found that at day 2 there continued to be an overcorrection with the infraspinatus remaining softer at this time point.

Indexed as

Elasticity Imaging TechniquesExerciseRotator CuffAdultFemaleHumansMaleProspective StudiesYoung AdultExercise recoveryMuscle injuryMuscle recoveryMuscle strainRepetitive muscle useUltrasound elastography

Identifiers

PMID40163286
PMCPMC12145367

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.