Evidence map›Paper›PMID 40163245›Full record

ReviewJournal of neuro-oncology2025

Resection of craniopharyngiomas: comparison between gross total resection and subtotal resection with adjuvant radiation.

Umberto Tosi, Theodore H Schwartz

Abstract readReviewComparative Study
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Umberto TosiDepartment of Neurological Surgery, Weill Cornell Medicine, New York, NY, USA. umt9001@nyp.org.ORCID http://orcid.org/0000-0003-0847-2400
Theodore H SchwartzDepartment of Neurological Surgery, Weill Cornell Medicine, New York, NY, USA. tedschwartz13@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe surgical treatment of craniopharyngiomas (CPs) remains a challenge, with significant variability in the literature.

methodswe therefore analyze current studies to demonstrate how the field has changed over the years.

resultsAchieving a gross total resection for these histologically benign lesions often poses significant difficulty based on their proximity, adherence, or invasion of adjacent critically important neuronal and vascular structures. In our historical literature, gross-total resection from transcranial surgery often carried high morbidity leading some to advocate for subtotal resection paired with postoperative radiotherapy as a preferable strategy. The advent of the extended endonasal endoscopic approach has led to a reconsideration of this tactic.

conclusionsIn this review, we discuss several of the studies that led to the current understanding of surgical options for craniopharyngiomas and discuss how the endonasal approach and more recent published results may modify surgical thinking.

Indexed as

CraniopharyngiomaNeurosurgical ProceduresPituitary NeoplasmsHumansRadiotherapy, AdjuvantCraniopharyngiomasEndoscopyGross-total resectionHypopituitarismRadiationSubtotal resectionSurgery

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.