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ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Surgical management of a giant glial hamartoma in a pediatric patient: a case report.

Guive Sharifi, Elham Paraandavaji, Shahin Naghizadeh, Yalda Nilipour, Mohammad Ali Kazemi, Sajjad Khanbabazadeh, Farzad Taghizadeh-Hesary

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Guive SharifiDepartment of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Elham ParaandavajiStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahin NaghizadehStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Yalda NilipourPediatric Pathology Research Center, Research Institute for Children'S Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad Ali KazemiDepartment of Radiology, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sajjad KhanbabazadehDivision of Vascular and Endovascular Neurosurgery, Faculty of Medicine, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran. sajjadkhanbabazadeh@yahoo.com.ORCID 0009-0006-5576-3058
Farzad Taghizadeh-HesarySchool of Medicine, ENT and Head and Neck Research Center, the Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran. farzadth89@gmail.com.ORCID 0000-0002-6195-2203

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlial hamartomas are benign growths of glial cells, and their management is challenging due to their rarity and variable presentation. We present a case of a giant glial hamartoma in a pediatric patient, incidentally discovered during routine imaging for a planned tonsillectomy. CASE DESCRIPTION: A 7-year-old boy with no prior neurological symptoms was found to have a large glial hamartoma in the right frontal lobe, measuring 67 mm in height and 50 mm in transverse diameter. Imaging studies revealed a hyperdense mass with internal calcifications on CT, hypointense on T1-weighted MRI, and hyperintense on T2-weighted MRI. Histopathology confirmed the diagnosis, showing benign glial cells, Rosenthal fibers, and eosinophilic granular bodies. A multidisciplinary team decided on surgical resection due to the tumor's size. The tumor was resected without complications, and postoperative recovery was uneventful. Follow-up MRIs at 4 months and 2 years post-surgery showed no residual tumor or recurrence.

conclusionsThis case underscores the role of radiological evaluation in identifying rare asymptomatic glial hamartomas and supports surgical resection to prevent complications. Comprehensive follow-up is essential for early detection of any recurrence.

Indexed as

Brain DiseasesBrain NeoplasmsHamartomaNeurogliaNeurosurgical ProceduresChildHumansMagnetic Resonance ImagingMaleGlial hamartomaPediatric neurosurgerySurgical resection

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.