Evidence map›Paper›PMID 40163158›Full record

ArticleNatural products and bioprospecting2025

Vibralactone derivatives isolated from co-cultures of the basidiomycetes Stereum hirsutum and Boreostereum vibrans.

Jinjuan Wei, Zhe-Xi Li, Gao-Ke Peng, Xinyang Li, He-Ping Chen, Ji-Kai Liu

Abstract read
In one paragraph

Article in Natural products and bioprospecting, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Synthetic study toward vibralactone.Beilstein journal of organic chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinjuan Wei *School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China.
Zhe-Xi Li *School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China.
Gao-Ke Peng *School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China.
Xinyang LiSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China.
He-Ping ChenSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China. chenhp@mail.scuec.edu.cn.ORCID http://orcid.org/0000-0003-0416-9535
Ji-Kai LiuSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China. liujikai@mail.scuec.edu.cn.

Funding

Fundamental Research Funds for the Central Universities, South-Central Minzu University CPT22033National Natural Science Foundation of China 82473810
6 · The paper itself

Abstract

The basidiomycetes Stereum hirsutum and Boreostereum vibrans are two fungi of the same genus. In this study, chemical investigation on the co-cultures of the two congeneric fungi led to the isolation of eleven new vibralactone derivatives, hirsutavibrins A-K (1-11). The structures of 1-11 were elucidated by extensive NMR and HRESIMS spectroscopic analysis, and computational methods. Hirsutavibrins A (1) and B (2) showed weak cytotoxicity against the human lung cancer cell line A549. Hirsutavibrin D (4) showed moderate anti-nitric oxide activity in murine monocytic RAW 264.7 macrophages. This work not only expands the members of vibralactone derivatives with variable configurations but also opens a new avenue for fungal co-culturing study between congeneric fungi.

Indexed as

BasidiomycetesBoreostereum vibransCo-cultureStereum hirsutumVibralactone derivatives

Identifiers

PMID40163158
PMCPMC11958929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.