Evidence map›Paper›PMID 40163068›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2025

Innovation in Providing Equitable Pre-exposure Prophylaxis Services in the United States: Expanding Access in Nontraditional Settings.

Joanne E Mantell, Laurie J Bauman, Stephen Bonett, Susan Buchbinder, Susie Hoffman, Erik D Storholm, Katryna McCoy, Christine T Rael, Ethan Cowan, Tatiana Gonzalez-Argoti and 5 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joanne E MantellHIV Center for Clinical and Behavioral Studies, Department of Psychiatry and the NYS Psychiatric Institute, Columbia University, New York, NY.
Laurie J BaumanPediatrics and Psychiatry and Behavioral Science, Albert Einstein College of Medicine, The Bronx, NY.
Stephen BonettSchool of Nursing, University of Pennsylvania, Philadelphia, PA.
Susan BuchbinderBridge HIV, San Francisco Department of Public Health, San Francisco, CA.
Susie HoffmanHIV Center for Clinical and Behavioral Studies, Departments of Psychiatry and Epidemiology, and the NYS Psychiatric Institute, Columbia University, New York, NY.
Erik D StorholmSchool of Public Health, San Diego State University, San Diego, CA.
Katryna McCoySchool of Nursing, University of North Carolina, Charlotte, NC.
Christine T RaelCollege of Nursing, Anschutz Medical Campus, University of Colorado, Aurora, CO.
Ethan CowanRutgers New Jersey Medical School, Newark, NJ.
Tatiana Gonzalez-ArgotiAlbert Einstein College of Medicine, The Bronx, NY.
Hussein SafaTelePreP Program, Einstein Healthcare Network, Philadelphia, PA.
Hyman ScottBridge HIV, San Francisco Department of Public Health, San Francisco, CA.
Kimberly Ling MurtaughDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA; and.
Natalie L WilsonUCSF School of Nursing, Community Health Systems, San Francisco, CA.
Albert LiuBridge HIV, San Francisco Department of Public Health, San Francisco, CA.

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
PrEP-3D: An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSMR01MH119956 · NIMH · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI BUCHBINDER, SUSAN · 2019 to 2023
$2.4M
PrEP-ED: PrEP Services in the Emergency Department for Hard-to-Reach PopulationsR34MH130267 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI COWAN, ETHAN ADRIAN, HOFFMAN, SUSIE · 2022 to 2022
$267k
NIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI045008NIAID NIH HHS P30 AI050410NIMH NIH HHS P30 MH043520NIMH NIH HHS P30 MH058107NIMH NIH HHS P30 MH062246NIMH NIH HHS R01 MH119956NIMH NIH HHS R34 MH130267
6 · The paper itself

Abstract

backgroundPre-exposure prophylaxis (PrEP) usage has slowly increased in the United States, but significant disparities persist across race, ethnicity, sex, gender, age, and geography. Determinants of PrEP inequities include stigma and medical mistrust, lack of patient-centered services, lack of access to clinical care, and organizational resistance to change-within a health care system that neglects these barriers.

methodsWe describe 5 implementation strategies to providing PrEP in nontraditional settings to underserved populations, using an equity-based approach to address key structural determinants. The alternative settings used in these Ending the HIV Epidemic projects (community-based organizations, telePrEP, mobile clinics, pharmacies, emergency departments) were chosen for the setting characteristics and their serving structurally underserved populations.

resultsCommunity-based organizations have earned trust within communities and can serve as hubs for comprehensive sexual health services, including PrEP. Telehealth, which expanded significantly because of COVID-19, can help overcome transportation and scheduling barriers to PrEP access. Mobile clinics can also broaden PrEP delivery by bringing tailored services directly to communities, often providing shorter wait times and extended hours. Pharmacists can prescribe PrEP in certain states through legislation or collaborative practice agreements, offering a convenient, community-based option. Emergency departments provide an alternative site for PrEP delivery, with the potential to reach individuals not currently engaged in regular care.

conclusionThese alternative PrEP approaches can expand options for accessing PrEP and alleviate key barriers to care in traditional settings, although they may not eliminate all inequities. Offering more choices increases the likelihood that a broader population will be reached, thereby enhancing overall access to PrEP.

Indexed as

Anti-HIV AgentsHealth Services AccessibilityHIV InfectionsPre-Exposure ProphylaxisCOVID-19FemaleHumansMaleTelemedicineUnited StatesAnti-HIV Agents

Identifiers

PMID40163068
PMCPMC12987501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.