Evidence map›Paper›PMID 40162942›Full record

Observational studyJournal of the American College of Cardiology2025

Survival Outcomes After Sudden Cardiac Arrest in Young Competitive Athletes From the United States.

Bradley J Petek, Timothy W Churchill, Nathaniel Moulson, Randi Delong, Mary Catherine Minnig, Stephanie A Kliethermes, Aaron L Baggish, Joseph J Maleszewski, Kristen L Kucera, Kimberly G Harmon and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of the American College of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Sudden cardiac arrest during endurance races: beyond final acceleration?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  3. RevisitingJournal of the American Heart Association · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bradley J PetekSports Cardiology Program, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon, USA.
Timothy W ChurchillDivision of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA; Cardiovascular Performance Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Nathaniel MoulsonDivision of Cardiology and Sports Cardiology BC, University of British Columbia, Vancouver, British Columbia, Canada.
Randi DelongDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Mary Catherine MinnigDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Stephanie A KliethermesDepartment of Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconsin, USA.
Aaron L BaggishSwiss Olympic Medical Center, Lausanne University Hospital (CHUV), Lausanne, Switzerland; Institute for Sport Science, University of Lausanne (ISSUL), Lausanne, Switzerland.
Joseph J MaleszewskiDepartment of Laboratory Medicine and Pathology, Mayo Clinic Rochester, Minnesota, USA.
Kristen L KuceraDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kimberly G HarmonDepartment of Family Medicine and Center for Sports Cardiology, University of Washington, Seattle, Washington, USA.
Jonathan A DreznerDepartment of Family Medicine and Center for Sports Cardiology, University of Washington, Seattle, Washington, USA. Electronic address: jdrezner@uw.edu.

Funding

Aortic Dilatation in Endurance Athletes: A Physiologic and Mechanistic StudyK23HL159262 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Timothy CHURCHILL · 2022 to 2026
$983k
NHLBI NIH HHS K23 HL159262
6 · The paper itself

Abstract

backgroundSudden cardiac arrest (SCA) is the leading cause of death among young competitive athletes during sports and exercise. A detailed analysis of survival outcomes should inform prevention strategies.

objectivesThe purpose of this study was to determine survival outcomes and trends following SCA among young competitive athletes in the United States and to explore outcomes based on race and exertional status.

methodsThis observational study identified cases of SCA among young competitive athletes through longitudinal surveillance by the National Center for Catastrophic Sports Injury Research from July 1, 2014, to June 30, 2023. Young athletes ≥11 years of age competing in middle school, high school, club, college, or semiprofessional/professional sports, and former athletes (within 1 year of participation) with SCA during exercise, rest, or sleep were included. The primary outcome was survival from SCA. Multivariable log binomial regression estimated survival proportion ratios by race and exertional status.

resultsA total of 641 athletes with SCA were identified during the 9-year study period (mean age 17 ± 3 years; 85% male). Overall survival was 49% (315 of 641). Survival from SCA occurring during exercise was 57% (275 of 481). The majority of cases were in high school athletes (61%), followed by college (15%) and middle school (12%) athletes. Overall survival (range 30%-66% per academic year; P = 0.007) and survival from exertional SCA (range 38%-72% per academic year; P = 0.03) both increased throughout the study period. Among exertional SCA events, survival was higher among athletes who experienced SCA during a game/competition vs practice/training (70% vs 53%; P = 0.001). Black race (RR: 0.63; 95% CI: 0.53-0.76), Other race (RR: 0.69; 95% CI: 0.50-0.94), and nonexertional SCA (RR: 0.43; 95% CI: 0.32-0.59) were associated with lower survival from SCA after adjusting for sex and level of competition.

conclusionsAlthough survival from SCA among young competitive athletes in the United States has improved in the last decade, important racial disparities in outcomes were observed warranting additional research and prevention strategies.

Indexed as

AthletesDeath, Sudden, CardiacAdolescentFemaleHumansLongitudinal StudiesMaleSurvival RateUnited StatesYoung Adultscreeningsudden cardiac arrestsudden cardiac deathyoung competitive athletes

Identifiers

PMID40162942
PMCPMC12396608

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.