Evidence map›Paper›PMID 40162795›Full record

ArticlemBio2025

Identification of the

Marcel Rühling, Fabio Schmelz, Alicia Kempf, Kerstin Paprotka, Martin J Fraunholz

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Staphylococcus aureus-vascular endothelium interactions: Mechanisms and therapeutic opportunities.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marcel RühlingChair of Microbiology, Julius-Maximilians-University Würzburg, Würzburg, Germany.ORCID 0009-0006-4757-5014
Fabio SchmelzChair of Microbiology, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Alicia KempfChair of Microbiology, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Kerstin PaprotkaChair of Microbiology, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Martin J FraunholzChair of Microbiology, Julius-Maximilians-University Würzburg, Würzburg, Germany.ORCID 0000-0002-4581-6244

Funding

Deutsche Forschungsgemeinschaft RTG2581Graduate School of Life Sciences, Julius-Maximilians-Universität Würzburg Career Development Fellowship
6 · The paper itself

Abstract

Virulence strategies of pathogens depend on interaction with host cells. The binding and activation of receptors located on the plasma membrane are crucial for the attachment to or pathogen internalization by host cells. Identifying host cell receptors is often difficult, and hence, the identity of many proteins that play important roles during host-pathogen interaction remains elusive. We developed a novel proximity labeling approach by decorating the opportunistic pathogen IMPORTANCE:

Indexed as

Endothelial CellsHost-Pathogen InteractionsMembrane ProteinsStaining and LabelingStaphylococcus aureusBacterial ProteinsCell MembraneHumansStaphylococcal InfectionsBacterial ProteinsMembrane Proteinshost receptor identificationproximity biotinylationStaphylococcus aureus

Identifiers

PMID40162795
PMCPMC12077161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.