ArticleMedical physics2025
Dosimetric impact of positional uncertainties and a robust optimization approach for rectal intensity-modulated brachytherapy.
Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Development and characterization of a prototype selenium-75 high dose rate brachytherapy source.Medical physics · 2025Article
- Dosimetric impact of positional uncertainties and a robust optimization approach for rectal intensity-modulated brachytherapy.Medical physics · 2025Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundIntensity-modulated brachytherapy (IMBT) employs rotating high-Z shields during treatment to decrease radiation in certain directions and conform the dose distribution to the target volume. Prototypes for dynamic IMBT have been proposed for prostate, cervical, and rectal cancer. PURPOSE: We considered two shielded applicators for IMBT rectal cancer treatment and investigated how rotational uncertainties in the shield angle and translational uncertainties in the source position affect plan evaluation criteria.
methodsThe effect of rotational errors of
resultsFor the largest investigated rotational error of
conclusionsWe have quantified the effect of rotational shield and translational source errors of various magnitudes on evaluation criteria for rectal IMBT. The robust optimization approach was generally not able to mitigate positional errors. However, it resulted in more homogeneous dwell times, which can be beneficial in conventional high-dose-rate brachytherapy to avoid hot spots around specific dwell positions.
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