Evidence map›Paper›PMID 40162303›Full record

ArticleJBMR plus2025

Prevention of glucocorticoid-induced impairment of bone metabolism-a randomized, placebo-controlled, single centre proof-of-concept clinical trial.

Giulia Gregori, Lisa Johansson, Lena Silberberg, Henrik Imberg, Per Magnusson, Marcus Lind, Mattias Lorentzon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giulia GregoriDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Osteoporosis Centre, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Lisa JohanssonDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Osteoporosis Centre, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Lena SilberbergDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Osteoporosis Centre, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Henrik ImbergStatistiska Konsultgruppen, SE-414 63 Gothenburg, Sweden.
Per MagnussonDepartment of Clinical Chemistry and Department of Biomedical and Clinical Sciences, Linköping University, SE-581 83 Linköping, Sweden.ORCID https://orcid.org/0000-0002-2123-7838
Marcus LindDepartment of Molecular and Clinical Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Mattias LorentzonDepartment of Internal Medicine and Clinical Nutrition, Sahlgrenska Osteoporosis Centre, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-0749-1431

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral glucocorticoid (GC) therapy rapidly and deleteriously affects bone metabolism and blood glucose regulation. The gut microbiota regulates bone metabolism and a prior study found that

Indexed as

blood glucosebone status indicesgut microbiotaoral glucocorticoid treatmentprobiotic

Identifiers

PMID40162303
PMCPMC11950668

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.