Evidence map›Paper›PMID 40162250›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Expanding cholera serosurveillance to vaccinated populations.

Forrest K Jones, Taufiqur R Bhuiyan, Damien M Slater, Ralph Ternier, Kian Robert Hutt Vater, Ashraful I Khan, Fahima Chowdhury, Kennia Visieres, Rajib Biswas, Mohammad Kamruzzaman and 10 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Forrest K JonesDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.ORCID 0000-0002-0914-6722
Taufiqur R BhuiyanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0003-3755-4763
Damien M SlaterDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.ORCID 0000-0002-1115-0894
Ralph TernierZanmi Lasante, Port au Prince, Haiti.
Kian Robert Hutt VaterDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.
Ashraful I KhanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Fahima ChowdhuryInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Kennia VisieresZanmi Lasante, Port au Prince, Haiti.
Rajib BiswasInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mohammad KamruzzamanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Edward T RyanDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.ORCID 0009-0005-0169-394X
Stephen B CalderwoodDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.ORCID 0000-0002-2083-7153
Regina C LaRocqueDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.ORCID 0000-0003-4558-0339
Richelle C CharlesDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.ORCID 0000-0002-8881-1849
Daniel T LeungDivision of Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0001-8401-0801
Justin LesslerDepartment of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA.ORCID 0000-0002-9741-8109
Louise C IversDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.ORCID 0000-0003-2314-9230
Firdausi QadriInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-8928-9888
Jason B HarrisDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.
Andrew S AzmanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.ORCID 0000-0001-8662-9077

Funding

Immune Responses to Vibrio cholerae infection and vaccination in HaitiR01AI099243 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B, IVERS, LOUISE C. · 2012 to 2022
$7.9M
Protecutive immunity to human cholera in BangladeshU01AI058935 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CALDERWOOD, STEPHEN B., RYAN, EDWARD T. · 2003 to 2014
$7.8M
Training program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4M
Antibody mediated protective immunity against choleraR01AI137164 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHARLES, RICHELLE C, HARRIS, JASON B · 2018 to 2022
$3.9M
O-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7M
Estimating Cholera Burden with Cross-sectional Immunologic DataR01AI135115 · NIAID · UNIVERSITY OF UTAH · PI LEUNG, DANIEL TED · 2018 to 2022
$3.4M
IMMUNE RESPONSES TO V. CHOLERAE INFECTION IN BANGLADESHU01HD039165 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI CALDERWOOD, STEPHEN B. · 2000 to 2002
$1.1M
Humoral and adaptive immune responses study in Vibrio cholerae infectionK43TW010362 · FIC · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI BHUIYAN, MD TAUFIQUR RAHMAN · 2016 to 2020
$359k
FIC NIH HHS D43 TW005572FIC NIH HHS K43 TW010362NIAID NIH HHS R01 AI099243NIAID NIH HHS R01 AI106878NIAID NIH HHS R01 AI135115NIAID NIH HHS R01 AI137164NIAID NIH HHS U01 AI058935NICHD NIH HHS U01 HD039165
6 · The paper itself

Abstract

Mass oral cholera vaccination campaigns targeted at subnational areas with high incidence are central to global cholera elimination efforts. Serological surveillance offers a complementary approach to address gaps in clinical surveillance in these regions. However, similar immune responses from vaccination and infection can lead to overestimates of incidence of infection. To address this, we analyzed antibody dynamics in infected and vaccinated individuals to refine seroincidence estimation strategies for partially vaccinated populations. We tested 757 longitudinal serum samples from confirmed

Identifiers

PMID40162250
PMCPMC11952589

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.