ArticlemedRxiv : the preprint server for health sciences2025
Expanding cholera serosurveillance to vaccinated populations.
Forrest K Jones, Taufiqur R Bhuiyan, Damien M Slater, Ralph Ternier, Kian Robert Hutt Vater, Ashraful I Khan, Fahima Chowdhury, Kennia Visieres, Rajib Biswas, Mohammad Kamruzzaman and 10 more
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In one paragraphArticle in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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1 · What the graph read from itWhat it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
20 authors.
Forrest K JonesDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.ORCID 0000-0002-0914-6722 Taufiqur R BhuiyanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0003-3755-4763 Ralph TernierZanmi Lasante, Port au Prince, Haiti.
Kian Robert Hutt VaterDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.
Ashraful I KhanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Fahima ChowdhuryInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Kennia VisieresZanmi Lasante, Port au Prince, Haiti.
Rajib BiswasInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mohammad KamruzzamanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Daniel T LeungDivision of Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0001-8401-0801 Justin LesslerDepartment of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA.ORCID 0000-0002-9741-8109 Firdausi QadriInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-8928-9888 Jason B HarrisDivision of Infectious Diseases, Massachusetts General Hospital, Boston, USA.
Andrew S AzmanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.ORCID 0000-0001-8662-9077 Funding
Immune Responses to Vibrio cholerae infection and vaccination in HaitiR01AI099243 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B, IVERS, LOUISE C. · 2012 to 2022
$7.9MProtecutive immunity to human cholera in BangladeshU01AI058935 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CALDERWOOD, STEPHEN B., RYAN, EDWARD T. · 2003 to 2014
$7.8MTraining program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4MAntibody mediated protective immunity against choleraR01AI137164 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHARLES, RICHELLE C, HARRIS, JASON B · 2018 to 2022
$3.9MO-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7MEstimating Cholera Burden with Cross-sectional Immunologic DataR01AI135115 · NIAID · UNIVERSITY OF UTAH · PI LEUNG, DANIEL TED · 2018 to 2022
$3.4MIMMUNE RESPONSES TO V. CHOLERAE INFECTION IN BANGLADESHU01HD039165 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI CALDERWOOD, STEPHEN B. · 2000 to 2002
$1.1MHumoral and adaptive immune responses study in Vibrio cholerae infectionK43TW010362 · FIC · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI BHUIYAN, MD TAUFIQUR RAHMAN · 2016 to 2020
$359kFIC NIH HHS D43 TW005572FIC NIH HHS K43 TW010362NIAID NIH HHS R01 AI099243NIAID NIH HHS R01 AI106878NIAID NIH HHS R01 AI135115NIAID NIH HHS R01 AI137164NIAID NIH HHS U01 AI058935NICHD NIH HHS U01 HD039165
6 · The paper itselfAbstract
Mass oral cholera vaccination campaigns targeted at subnational areas with high incidence are central to global cholera elimination efforts. Serological surveillance offers a complementary approach to address gaps in clinical surveillance in these regions. However, similar immune responses from vaccination and infection can lead to overestimates of incidence of infection. To address this, we analyzed antibody dynamics in infected and vaccinated individuals to refine seroincidence estimation strategies for partially vaccinated populations. We tested 757 longitudinal serum samples from confirmed
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PMID40162250
PMCPMC11952589
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