Evidence map›Paper›PMID 40162147›Full record

ArticleOxford medical case reports2025

Oral contraceptive pill-induced esophagitis: a rare cause of pill esophagitis in a Rwandan woman.

Gordon P Bensen, Matthew R Bryan, Esther Nishimwe, Bao Sean Nguyen, Kenechukwu Chudy-Onwugaje

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gordon P BensenHarvard Medical School, 25 Shattuck Street, Boston, MA 02115, United States.ORCID https://orcid.org/0000-0002-1605-1465
Matthew R BryanHarvard Medical School, 25 Shattuck Street, Boston, MA 02115, United States.ORCID https://orcid.org/0009-0004-6002-4052
Esther NishimweGisenyi District Hospital, Gisenyi, Rubavu District, 00000, Rwanda.
Bao Sean NguyenDivision of Digestive Diseases, UCLA Health, 200 Medical Plaza, Los Angeles, CA 90024, United States.
Kenechukwu Chudy-OnwugajeDepartment of Medicine, Memorial Hospital Belleville, 4500 Memorial Drive, Belleville, IL 62226, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of oral contraceptive pill (OCP)-induced esophagitis in a 43-year-old Rwandan woman. She presented with epigastric and retrosternal pain and reported daily use of a combined OCP containing ethinyl estradiol and levonorgestrel. Upper endoscopy revealed a solitary, clean-based esophageal ulcer. Histopathologic evaluation excluded infectious causes, and she improved with proton pump inhibitor therapy and modification of pill consumption habits. This is the first reported case of OCP-induced esophagitis on the African continent and the fifth case overall, and it highlights the importance of awareness of this rare gastrointestinal adverse effect of a commonly used class of drugs, particularly in an area of the world that is promoting the increased uptake of female contraception as a tool for family planning.

Indexed as

Esophageal ulcerEsophagusoral contraceptive pill (OCP)pill esophagitis

Identifiers

PMID40162147
PMCPMC11952898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.