Evidence map›Paper›PMID 40162073›Full record

ArticleToxicology reports2025

Antimutagenic effects of 2,6-Dimethylpyridine-N-oxide using fluctuation ames test.

Olesia Vasetska, Volodymyr Bubalo, Tetyana Usenko, Petro Zhminko, Mykola Prodanchuk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olesia VasetskaL.I. Medved's Research Center of Preventive Toxicology, Food and Chemical Safety, Ministry of Health Ukraine, SE, Laboratory of Experimental Toxicology and Mutagenesis, Kyiv, Ukraine.
Volodymyr BubaloL.I. Medved's Research Center of Preventive Toxicology, Food and Chemical Safety, Ministry of Health Ukraine, SE, Laboratory of Experimental Toxicology and Mutagenesis, Kyiv, Ukraine.
Tetyana UsenkoL.I. Medved's Research Center of Preventive Toxicology, Food and Chemical Safety, Ministry of Health Ukraine, SE, Laboratory of Experimental Toxicology and Mutagenesis, Kyiv, Ukraine.
Petro ZhminkoL.I. Medved's Research Center of Preventive Toxicology, Food and Chemical Safety, Ministry of Health Ukraine, SE, Laboratory of Experimental Toxicology and Mutagenesis, Kyiv, Ukraine.
Mykola ProdanchukL.I. Medved's Research Center of Preventive Toxicology, Food and Chemical Safety, Ministry of Health Ukraine, SE, Laboratory of Experimental Toxicology and Mutagenesis, Kyiv, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mutagenic potential of chemical agents is a significant concern in the field of genetic toxicology. The 2,6-Dimethylpyridine-N-oxide is believed to have antimutagenic properties, which could be beneficial for applications in pharmaceutical and environmental sciences. This study aims to evaluate the antigenotoxic potential of 2,6-Dimethylpyridine-N-oxide using the fluctuation Ames test, a reliable method for detecting mutagenic effect. Specifically, the Ames assay was conducted with preincubation in a suspension of reversion Salmonella bacteria. The experimental approach utilized

Indexed as

2.6-Dimethylpyridine-N-oxideAntimutagenic effectFluctuation Ames Test

Identifiers

PMID40162073
PMCPMC11950738

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.