Evidence map›Paper›PMID 40161999›Full record

ArticleJournal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America2025

Fast Variational Inference for Bayesian Factor Analysis in Single and Multi-Study Settings.

Blake Hansen, Alejandra Avalos-Pacheco, Massimiliano Russo, Roberta De Vito

Abstract read
In one paragraph

Article in Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Blake HansenDepartment of Biostatistics, Brown University.
Alejandra Avalos-PachecoApplied Statistics Research Unit, TU Wien, Harvard-MIT Center for Regulatory Science, Harvard Medical School.
Massimiliano RussoDepartment of Statistics, The Ohio State University.
Roberta De VitoDepartment of Biostatistics and Data Science Institute, Brown University.

Funding

The role of Sirtuins in neurodegenerative diseaseP20GM109035 · NIGMS · BROWN UNIVERSITY · PI WONG, IAN Y · 2016 to 2025
$22.6M
Statistical methods for cancer mutational signaturesR01CA262710 · NCI · DANA-FARBER CANCER INST · PI PARMIGIANI, GIOVANNI LUIGI · 2021 to 2025
$1.8M
NCI NIH HHS R01 CA262710NIGMS NIH HHS P20 GM109035
6 · The paper itself

Abstract

Factors models are commonly used to analyze high-dimensional data in both single-study and multi-study settings. Bayesian inference for such models relies on Markov Chain Monte Carlo (MCMC) methods, which scale poorly as the number of studies, observations, or measured variables increase. To address this issue, we propose new variational inference algorithms to approximate the posterior distribution of Bayesian latent factor models using the multiplicative gamma process shrinkage prior. The proposed algorithms provide fast approximate inference at a fraction of the time and memory of MCMC-based implementations while maintaining comparable accuracy in characterizing the data covariance matrix. We conduct extensive simulations to evaluate our proposed algorithms and show their utility in estimating the model for high-dimensional multi-study gene expression data in ovarian cancers. Overall, our proposed approaches enable more efficient and scalable inference for factor models, facilitating their use in high-dimensional settings. An R package VIMSFA implementing our methods is available on GitHub (github.com/blhansen/VI-MSFA).

Indexed as

Factor AnalysisMulti-StudyShrinkage priorVariational Bayes

Identifiers

PMID40161999
PMCPMC11949465

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.