Evidence map›Paper›PMID 40161909›Full record

ArticleIndian journal of anaesthesia2025

Pectoral nerve block and pecto-intercostal fascial block versus thoracic paravertebral block for postoperative analgesia in modified radical mastectomy: A randomised controlled trial.

Adarsh M Sheshagiri, Ajeet Kumar, Chandni Sinha, Abhyuday Kumar, Poonam Kumari, Amarjeet Kumar, Chandan Jha

Abstract read
In one paragraph

Article in Indian journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adarsh M SheshagiriDepartment of Anaesthesiology, Critical Care and Pain Medicine, AIIMS, New Delhi, India.ORCID https://orcid.org/0009-0002-3597-7252
Ajeet KumarDepartment of Anaesthesia, AIIMS, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-1464-6684
Chandni SinhaDepartment of Anaesthesia, AIIMS, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-4107-2671
Abhyuday KumarDepartment of Anaesthesia, AIIMS, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-9247-6713
Poonam KumariDepartment of Anaesthesia, AIIMS, Patna, Bihar, India.ORCID https://orcid.org/0000-0003-0118-2187
Amarjeet KumarDepartment of Anaesthesia, AIIMS, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-4272-5750
Chandan JhaDepartment of Surgery, AIIMS, Patna, Bihar, India.ORCID https://orcid.org/0000-0003-0968-3269

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Modified radical mastectomy (MRM) is associated with persistent postoperative pain. Paravertebral block (PVB) is the gold standard for postoperative analgesia. A pecto-intercostal fascial plane (PIFB) block added to the pectoral nerve block (Pecs) may provide effective analgesia. This trial aimed to compare the analgesic efficacy of Pecs-PIFB with PVB. Methods: Fifty American Society of Anesthesiologists (ASA) I/II patients scheduled for MRM were randomly assigned to receive either Pecs-PIFB block with 30 mL for Pecs block and 15 mL for PIFB or PVB block with 20 mL (0.2% ropivacaine). Postoperatively, intravenous (IV) morphine was administered through a patient-controlled analgesia (PCA) pump. The primary outcome was to compare the time to the first demand dose of rescue analgesic. The secondary outcomes were postoperative 24-hour opioid consumption, pain scores (30 mins and 1, 2, 4, 6, 12, and 24 h), patient satisfaction score (24 h), and block-related complications. The unpaired Results: Patients in the Group Pecs-PIFB had an increased median time to first demand dose: 440 [interquartile range (IQR): 360-540] versus 340 (IQR: 180-360) minutes ( Conclusion: Compared to thoracic PVB, the combination of Pecs and PIFB block prolonged the duration of analgesia and decreased postoperative opioid consumption in patients undergoing MRM surgeries. There was no statistical increase in complications in patients receiving this block.

Indexed as

Modified radical mastectomymorphineparavertebral blockPecto-intercostal fascial planepectoral nervepectoral nerve blockPIFBpostoperative pain

Identifiers

PMID40161909
PMCPMC11952172

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.