Evidence map›Paper›PMID 40161869›Full record

ArticleEJHaem2025

Lymphocytic Variant Hypereosinophilic Syndrome: Case Series From a Tertiary Referral Center in Canada.

Xiu Qing Wang, Kevin Shopsowitz, Jack Lofroth, Xuehai Wang, Erica Peterson, Andrew P Weng, Luke Y C Chen

Abstract read
In one paragraph

Article in EJHaem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiu Qing WangDepartment of Pathology and Laboratory Medicine University of British Columbia Vancouver British Columbia Canada.ORCID https://orcid.org/0000-0003-2318-102X
Kevin ShopsowitzDepartment of Pathology and Laboratory Medicine University of British Columbia Vancouver British Columbia Canada.
Jack LofrothFaculty of Medicine University of British Columbia Vancouver British Columbia Canada.
Xuehai WangDepartment of Pathology and Laboratory Medicine University of British Columbia Vancouver British Columbia Canada.
Erica PetersonDivision of Hematology Dalhousie University Halifax Nova Scotia Canada.
Andrew P WengDepartment of Pathology and Laboratory Medicine University of British Columbia Vancouver British Columbia Canada.
Luke Y C ChenDivision of Hematology Dalhousie University Halifax Nova Scotia Canada.ORCID https://orcid.org/0000-0002-9551-2951

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lymphocytic variant hypereosinophilic syndrome (L-HES) is a rare disorder characterized by persistent eosinophilia driven by aberrant T-cell populations. Diagnosis remains challenging due to the lack of standardized diagnostic criteria. Methods: We retrospectively analyzed 18 patients diagnosed with L-HES between 2016 and 2023. Comprehensive flow cytometry was performed on peripheral blood samples. Results: Nine patients demonstrated the classic sCD3 Conclusion: Our study highlights the diverse immunophenotypic spectrum of L-HES, emphasizing the importance of comprehensive flow cytometry analysis for accurate diagnosis.

Indexed as

eosinophiliahypereosinophilic syndromelymphocyte immunophenotypinglymphocytic hypereosinophilic syndromeT‐cell receptor gene rearrangement

Identifiers

PMID40161869
PMCPMC11955013

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.