Evidence map›Paper›PMID 40161778›Full record

ArticlebioRxiv : the preprint server for biology2025

BR-Bodies Facilitate Adaptive Responses and Survival During Copper Stress in

Christie Passos, Dylan Tomares, Hadi Yassine, Wade Schnorr, Hannah Hunter, Helena K Wolfe-Feichter, James Velier, Kathryn G Dzurik, Julia Grillo, Alisa Gega and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Christie PassosDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.
Dylan TomaresDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.
Hadi YassineDepartment of Biological Sciences, Wayne State University, Detroit, MI, 48202, USA.
Wade SchnorrDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.
Hannah HunterDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.
Helena K Wolfe-FeichterDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.
James VelierDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.
Kathryn G DzurikDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.
Julia GrilloDepartment of Biological Sciences, Wayne State University, Detroit, MI, 48202, USA.
Alisa GegaDepartment of Biological Sciences, Wayne State University, Detroit, MI, 48202, USA.
Sunil SaxenaDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.ORCID 0000-0001-9098-6114
Jared SchraderDepartment of Biological Sciences, Wayne State University, Detroit, MI, 48202, USA.ORCID 0000-0002-5728-5882
W Seth ChildersDepartment of Chemistry, University of Pittsburgh, Pittsburgh, 15260, USA.ORCID 0000-0003-1160-7767

Funding

Mechanisms of Non-Shine-Dalgarno Translation InitiationR35GM124733 · NIGMS · WAYNE STATE UNIVERSITY · PI Jared Michael Schrader · 2017 to 2026
$3.6M
Biomolecular condensates as organizers of mRNA decay in bacteriaR01GM136863 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William Seth Childers · 2020 to 2026
$1.9M
NIGMS NIH HHS R01 GM136863NIGMS NIH HHS R35 GM124733
6 · The paper itself

Abstract

Microbes must rapidly adapt to environmental stresses, including toxic heavy metals like copper, by sensing and mitigating their harmful effects. Here, we demonstrate that the phase separation properties of bacterial ribonucleoprotein bodies (BR-bodies) enhance

Identifiers

PMID40161778
PMCPMC11952403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.