Evidence map›Paper›PMID 40161602›Full record

ArticlebioRxiv : the preprint server for biology2025

The ectodermal loss of ARHGAP29 alters epithelial morphology and organization and disrupts murine palatal development.

Emily Adelizzi, Lindsey Rhea, Campbell Mitvalsky, Samuel Pek, Bethany Doolittle, Martine Dunnwald

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Emily Adelizzi
Lindsey Rhea
Campbell Mitvalsky
Samuel Pek
Bethany Doolittle
Martine Dunnwald

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orofacial clefts, including cleft palate (CP), are among the most common types of birth defects. CP specifically, results from a failure of palatal shelf fusion during development. Previous studies have shown that mutations in Summary statement: This study in mice is the first direct evidence that ARHGAP29 is essential for proper palatal elevation and fusion. Loss of

Identifiers

PMID40161602
PMCPMC11952475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.