Evidence map›Paper›PMID 40161548›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Dementia ascertainment in India and development of nation-specific cutoffs: A machine learning and diagnostic analysis.

Danny Maupin, Hongxin Gao, Emma Nichols, Alden Gross, Erik Meijer, Haomiao Jin

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danny MaupinSchool of Health Sciences Faculty of Health and Medical Sciences University of Surrey, Stag Hill University Campus Guildford UK.ORCID https://orcid.org/0000-0002-0510-6627
Hongxin GaoSchool of Health Sciences Faculty of Health and Medical Sciences University of Surrey, Stag Hill University Campus Guildford UK.
Emma NicholsCenter for Economic and Social Research University of Southern California VPD Los Angeles California USA.
Alden GrossDepartment of Epidemiology Bloomberg School of Public Health Johns Hopkins University Baltimore Maryland USA.
Erik MeijerCenter for Economic and Social Research University of Southern California VPD Los Angeles California USA.
Haomiao JinSchool of Health Sciences Faculty of Health and Medical Sciences University of Surrey, Stag Hill University Campus Guildford UK.

Funding

Integrting Information About Aging SurveysR01AG030153 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sara Adar, Alden L. Gross · 2007 to 2026
$41.7M
Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
Mega Meta Data Set of the Health and Retirement Surveys Around the WorldRC2AG036619 · NIA · RAND CORPORATION · PI KAPTEYN, ARIE · 2009 to 2010
$2.0M
Archiving & Creating User Friendly Data: the Longitudinal Aging Survey in IndiaR03AG043052 · NIA · RAND CORPORATION · PI LEE, JINKOOK · 2012 to 2012
$95k
NIA NIH HHS R01 AG030153NIA NIH HHS R01 AG051125NIA NIH HHS R03 AG043052NIA NIH HHS RC2 AG036619
6 · The paper itself

Abstract

Introduction: Cognitive assessments are useful in ascertaining dementia but may be influenced by patient characteristics. India's distinct culture and demographics warrant investigation into population-specific cutoffs. Methods: Data were utilized from the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia ( Results: The Informant Questionnaire of Cognitive Decline in the Elderly (IQCODE) and Hindi Mini-Mental State Examination (HMSE) were identified as the most impactful assessments with optimal cutoffs of 3.8 and 25, respectively. Discussion: An ML assessment of clinician dementia ratings identified IQCODE and HMSE to be the most impactful assessments. Optimal cutoffs of 3.8 and 25 were identified and performed excellently in the overall sample, though did decrease in specific, more difficult-to-diagnose subgroups. Highlights: Pioneers use of explainable artificial intelligence in the diagnosis of dementia.Creates assessment cutoffs specific to the nation of India.Highlights differences in cutoffs across nations.

Indexed as

agingassessmentcognitive declineexplainable machine learningpublic health

Identifiers

PMID40161548
PMCPMC11952995

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.