Evidence map›Paper›PMID 40161500›Full record

ReviewFrontiers in pediatrics2025

Microbiota modulation for infectious complications following allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies.

Wei Dai, Xiaofan Chen, Huanhuan Zhou, Ning Liu, Mengdi Jin, Zhi Guo

Abstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei Dai *Department of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Xiaofan Chen *Department of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Huanhuan Zhou *Department of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Ning Liu *Department of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Mengdi JinDepartment of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Zhi GuoDepartment of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intervention of microbiota modulation in the treatment of infection complications after allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies has shown potential benefits. Through the use of probiotics, prebiotics, synbiotics, and fecal microbiota transplantation (FMT), these interventions modulate the gut microbiota and enhance immune function to prevent and treat infections. They have been shown to reduce the incidence of diarrhea and intestinal infections, mitigate the issue of antibiotic resistance, and promote the recovery of gut microbiota. Future research is needed to further assess the safety and efficacy of these interventions and to establish standardized treatment protocols.

Indexed as

allogeneic hematopoietic stem cell transplantationgut microbiotainfection complicationsmicrobiota modulationpediatric hematological malignancies

Identifiers

PMID40161500
PMCPMC11952122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.