ArticleCureus2025
Microneedling Technique With Topical Vitamin C for Gingival Depigmentation Enhancing Gingival Aesthetics: A Longitudinal Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Comparative evaluation of microneedling technique and diode laser in gingival depigmentation: A prospective randomized study.Journal of clinical and experimental dentistry · 2026Review
- Clinical and patient-reported outcomes of microneedling with ascorbic acid versus scalpel technique for gingival depigmentation: A randomized clinical trial.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction As the focus on dental aesthetics intensifies, contemporary cosmetic dentistry seeks to establish an equilibrium between teeth and gums. Gingival hyperpigmentation, resulting from excessive melanin accumulation, can impact individuals regardless of age or gender and frequently gives rise to aesthetic apprehensions. Microneedling combined with topical vitamin C is a promising new method for improving gum appearance, particularly for reducing gingival hyperpigmentation caused by excess melanin. Microneedling is less expensive, more versatile, and promotes faster healing than traditional procedures like lasers or surgery. Materials and methods A study with 10 participants at the Karnavati School of Dentistry demonstrated significant pigmentation reduction. A paste was made with powdered ascorbic acid and a liquid ampule solution and applied with a Derma Pen (Dr. Pen Ultima A1, C Cube Advanced Technologies, India), which is a rechargeable pen-like instrument with 24-36 adjustable needles (0.25 mm to 2 mm) and five-speed settings. The gadget enables multi-directional treatment, and its disposable needle tips assure clean use with several patients. Results A significant decrease in melanin pigmentation was observed across all age groups, but anatomical challenges, such as irregular gingival contours, hampered results in some cases. Conclusion Microneedling is a safe and effective option for improving gingival aesthetics. As the technique evolves, it has the potential for broader applications.
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Registered trials
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