ReviewSleep advances : a journal of the Sleep Research Society2025
REM refines and rescues memory representations: a new theory.
Review in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Invertebrate brains as diversified models for understanding sleep mechanisms and function.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Theta oscillations tag episodic memories for sleep-dependent consolidation.PLoS biology · 2026Article
- REM sleep favors the restructuring of problem-related semantic associations.Communications biology · 2026Article
- Recovery sleep after total sleep deprivation preserves neutral and enhances emotional declarative memory.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Reflecting on 2025. Anticipating 2026.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Festschrift in honor of Dr. Robert Stickgold, pioneer in sleep, memory, and dream research.Sleep advances : a journal of the Sleep Research Society · 2026Article
- MRI methods for the study of central nervous system involvement in autonomic function.Frontiers in network physiology · 2026Review
- Sleep in neurodegenerative diseases: A focus on melatonin, melanin-concentrating hormone and orexin.Journal of neuroendocrinology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Despite extensive evidence on the roles of nonrapid eye movement (NREM) and REM sleep in memory processing, a comprehensive model that integrates their complementary functions remains elusive due to a lack of mechanistic understanding of REM's role in offline memory processing. We present the REM Refining and Rescuing (RnR) Hypothesis, which posits that the principal function of REM sleep is to increase the signal-to-noise ratio within and across memory representations. As such, REM sleep selectively enhances essential nodes within a memory representation while inhibiting the majority (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.