ArticleFrontiers in nutrition2025
Joint association of sleep duration and depression with new-onset hearing loss: a national cohort study.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Article
- Measuring and decomposing inequalities in intrinsic capacity among older adults in china: from an urban-rural divide perspective.Aging clinical and experimental research · 2025Article
- Sleep Disturbances Associated With Hidden Hearing Loss: Insights From Human Data and a Mouse Model of Sleep Fragmentation.Brain and behavior · 2025Observational
- Association between the depression and cardiovascular risk in arthritis patients: a prospective cohort study from the CHARLS database.Frontiers in immunology · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hearing loss, a global health burden, is closely associated with depression and sleep disorders. However, the combined effects of sleep duration and depression on hearing loss risk remain unclear. Methods: Data from the China Health and Retirement Longitudinal Study (CHARLS) were analyzed, including 6,374 adults aged 45 and older. Cox proportional hazards models assessed the relationship between depression, sleep duration, and hearing loss. Mediation analysis explored the potential mediating roles of CESD-10 score and sleep duration on new-onset hearing loss. Subgroup analyses by age, sex, and BMI were also conducted. Results: Over a 7-year follow-up, 1,422 participants developed hearing loss. Both short sleep duration and high CESD-10 scores were independently associated with increased risk of hearing loss. Participants with long sleep duration but depression had a hazards ratio (HR) of 1.59 (95% CI: 1.35, 1.87) for hearing loss. Mediation analysis showed that sleep duration mediated 10.1% of the association between CESD-10 score and hearing loss, while CESD-10 score mediated 70.8% of the relationship between sleep duration and hearing loss. Conclusion: This study highlights the significant and interconnected roles of sleep duration and depression in the development of hearing loss. Interventions addressing both sleep and depression may offer more effective strategies for preventing and managing hearing loss.
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