ArticleCureus2025
Alpha-Gal Syndrome: An Emerging Tick-Borne Allergy to Red Meat.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alpha-gal syndrome (AGS) is a delayed-onset food allergy triggered by an immune response to galactose-α-1,3-galactose (alpha-gal), a carbohydrate associated with Lone Star tick bites. A 45-year-old female presented with a 9-month history of nausea and abdominal pain consistently associated with red meat consumption. Initial workup, including routine labs, imaging, and endoscopy, was unremarkable, but specific IgE testing confirmed AGS. Management included strict avoidance of red meat, carrying an epinephrine auto-injector, and referral to an allergist for education and long-term care. This case highlights the diagnostic challenges posed by the delayed reaction and the importance of dietary vigilance and emergency preparedness. Increased awareness of AGS is essential, especially in regions where tick exposure is prevalent.
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