Evidence map›Paper›PMID 40161072›Full record

ArticleCureus2025

Characterizing the Association Between Asthma and Clinical Outcomes in Emergency Department Patients With Symptomatic COVID-19.

Bachar Al Mazloum, Harriet Richardson, Yingwei Peng, Brian Rowe, Corinne M Hohl, Vlad Latiu, Dryden Chadwick, Kavish Chandra, Steven C Brooks

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bachar Al MazloumDepartment of Public Health Sciences, Queen's University, Kingston, CAN.
Harriet RichardsonDepartment of Public Health Sciences, Divisions of Cancer Care and Epidemiology and Canadian Cancer Trials Group, Cancer Research Institute, Queen's University, Kingston, CAN.
Yingwei PengDepartment of Public Health Sciences, Department of Mathematics and Statistics, Division of Cancer Care and Epidemiology, Cancer Research Institute, Queen's University, Kingston, CAN.
Brian RoweEmergency Mecicine, University of Alberta, Edmonton, CAN.
Corinne M HohlDepartment of Emergency, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, University of British Columbia, Faculty of Medicine, Vancouver, CAN.
Vlad LatiuDepartment of Emergency Medicine, Queen's University, Kingston, CAN.
Dryden ChadwickDepartment of Public Health Sciences, Queen's University, Kingston, CAN.
Kavish ChandraDepartment of Emergency Medicine, Dalhousie Medicine New Brunswick, Dalhousie, CAN.
Steven C BrooksDepartment of Emergency Medicine, Queen's University, Kingston, CAN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few studies have investigated the risks of developing intubation and death in patients seen in the emergency department (ED) with COVID-19 and pre-existing asthma. We conducted a retrospective cohort study using data from the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) from March 1st, 2020, to December 31st, 2021. Inclusion criteria were age ≥18 and a positive SARS-CoV-2 test. The primary outcome was a composite of intubation or death, and the secondary outcome was severe COVID-19, as defined by the World Health Organization. Multivariable modified Poisson regression was used to assess the association between asthma and outcomes, adjusted for possible confounding. Out of 38,139 patients, 2,826 (7.41%) had asthma, and 17.1% were using inhaled corticosteroids (ICS). The study found no significant evidence suggesting an association between asthma and intubation or death in the hospital (relative risk (RR): 0.97; 95% CI: 0.86-1.1). The highest risk group for the primary outcome was patients aged 80+ years (RR: 10.54; 95% CI: 7.01-15.85), compared to the reference group 18-29 years. Users of ICS agents had a slightly higher risk of the primary outcome compared to non-ICS users (RR: 1.12; 95% CI: 1.01-1.25).

Indexed as

asthmacovid-19emergency departmentinhaled corticosteroidsobservational studysevere acute respiratory syndrome coronavirus 2

Identifiers

PMID40161072
PMCPMC11949855

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.